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上消化道腺癌中血型与HER-2状态之间缺乏相关性。

Lack of correlation between blood group and HER-2 status in adenocarcinomas of the upper gastrointestinal tract.

作者信息

Hejna Michael, Birner Peter, Preusser Matthias, Thallinger Christiane M R, Worel Nina, Asari Reza, Dolak Werner, Schmid Rainer, Schoppmann Sebastian F, Raderer Markus

机构信息

Departments of Internal Medicine I, Medical University of Vienna, A-1090 Vienna, Austria ; Comprehensive Cancer Center, Medical University of Vienna, A-1090 Vienna, Austria.

Pathology, Medical University of Vienna, A-1090 Vienna, Austria ; Comprehensive Cancer Center, Medical University of Vienna, A-1090 Vienna, Austria.

出版信息

Mol Clin Oncol. 2013 Nov;1(6):1079-1083. doi: 10.3892/mco.2013.181. Epub 2013 Sep 12.

DOI:10.3892/mco.2013.181
PMID:24649296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3915671/
Abstract

The assessment of the human epidermal growth factor receptor-2 (HER-2) status has become a routine diagnostic procedure for patients with advanced-stage gastroesophageal adenocarcinoma. The aim of this study was to evaluate the possible correlation between the HER-2 status and the ABO blood group. HER-2 status determination and routine ABO typing was performed according to current standards. We evaluated the correlation between the HER-2 status and the ABO and Rhesus (Rh) system in 100 consecutive patients with adenocarcinoma of the upper gastrointestinal tract. There were no significant differences between HER-2 status and ABO and Rh system. Furthermore, no correlation was observed between the HER-2 status and the ABO and Rh type in patients with adenocarcinoma of the upper gastrointestinal tract.

摘要

人表皮生长因子受体2(HER-2)状态评估已成为晚期胃食管腺癌患者的常规诊断程序。本研究的目的是评估HER-2状态与ABO血型之间可能存在的相关性。HER-2状态测定和常规ABO血型鉴定均按照现行标准进行。我们评估了100例连续的上消化道腺癌患者中HER-2状态与ABO及恒河猴(Rh)系统之间的相关性。HER-2状态与ABO及Rh系统之间无显著差异。此外,在上消化道腺癌患者中,未观察到HER-2状态与ABO及Rh血型之间存在相关性。

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本文引用的文献

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Lack of any relationship between ABO and Rh blood groups and clinicopathological features in patients with gastrointestinal stromal tumors: Turkish Oncology Group.ABO血型和Rh血型与胃肠道间质瘤患者临床病理特征之间不存在任何关联:土耳其肿瘤学组
Asian Pac J Cancer Prev. 2012;13(8):4129-31.
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ABO and Rh blood groups frequency in women with HER2 positive breast cancer.HER2阳性乳腺癌女性的ABO和Rh血型频率
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Blood type, hormone receptor status, HER2/neu status, and survival in breast cancer: a retrospective study exploring relationships in a phenotypically well-defined cohort.血型、激素受体状态、HER2/neu状态与乳腺癌生存情况:一项在表型明确队列中探索关系的回顾性研究
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Am J Epidemiol. 2010 Dec 1;172(11):1280-5. doi: 10.1093/aje/kwq299. Epub 2010 Oct 11.
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