上消化道腺癌中血型与HER-2状态之间缺乏相关性。
Lack of correlation between blood group and HER-2 status in adenocarcinomas of the upper gastrointestinal tract.
作者信息
Hejna Michael, Birner Peter, Preusser Matthias, Thallinger Christiane M R, Worel Nina, Asari Reza, Dolak Werner, Schmid Rainer, Schoppmann Sebastian F, Raderer Markus
机构信息
Departments of Internal Medicine I, Medical University of Vienna, A-1090 Vienna, Austria ; Comprehensive Cancer Center, Medical University of Vienna, A-1090 Vienna, Austria.
Pathology, Medical University of Vienna, A-1090 Vienna, Austria ; Comprehensive Cancer Center, Medical University of Vienna, A-1090 Vienna, Austria.
出版信息
Mol Clin Oncol. 2013 Nov;1(6):1079-1083. doi: 10.3892/mco.2013.181. Epub 2013 Sep 12.
The assessment of the human epidermal growth factor receptor-2 (HER-2) status has become a routine diagnostic procedure for patients with advanced-stage gastroesophageal adenocarcinoma. The aim of this study was to evaluate the possible correlation between the HER-2 status and the ABO blood group. HER-2 status determination and routine ABO typing was performed according to current standards. We evaluated the correlation between the HER-2 status and the ABO and Rhesus (Rh) system in 100 consecutive patients with adenocarcinoma of the upper gastrointestinal tract. There were no significant differences between HER-2 status and ABO and Rh system. Furthermore, no correlation was observed between the HER-2 status and the ABO and Rh type in patients with adenocarcinoma of the upper gastrointestinal tract.
人表皮生长因子受体2（HER-2）状态评估已成为晚期胃食管腺癌患者的常规诊断程序。本研究的目的是评估HER-2状态与ABO血型之间可能存在的相关性。HER-2状态测定和常规ABO血型鉴定均按照现行标准进行。我们评估了100例连续的上消化道腺癌患者中HER-2状态与ABO及恒河猴（Rh）系统之间的相关性。HER-2状态与ABO及Rh系统之间无显著差异。此外，在上消化道腺癌患者中，未观察到HER-2状态与ABO及Rh血型之间存在相关性。
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