Slater G, Itzkowitz S, Azar S, Aufses A H
Department of Surgery, Mount Sinai Medical Center, New York, New York 10029.
Dis Colon Rectum. 1993 Jan;36(1):5-7. doi: 10.1007/BF02050293.
There is no specific association established between colorectal cancer and blood group type. In this study, the distribution of ABO and Rh blood groups was studied in 838 patients with colorectal cancer. There was no difference in distribution of ABO blood groups between patients who were Rh+ and Rh-. There was no difference in ABO blood group or Rh factor and tumor location. The highest A/O ratio was found in rectal cancer. Although there was no difference in stage distribution for each ABO blood group, there was a significant difference between the Rh+ and Rh- groups (P < 0.037). It is not clear, however, whether the prognosis is different between the two groups since there were more early tumors as well as incurable tumors in the Rh- group. All patients with synchronous cancer were Rh+. Further studies on blood group antigens are needed to elucidate the relationship between these antigens and colorectal cancer.
结直肠癌与血型之间未建立特定关联。在本研究中，对838例结直肠癌患者的ABO和Rh血型分布进行了研究。Rh阳性和Rh阴性患者的ABO血型分布无差异。ABO血型或Rh因子与肿瘤位置无差异。直肠癌中A/O比值最高。虽然各ABO血型的分期分布无差异，但Rh阳性和Rh阴性组之间存在显著差异（P < 0.037）。然而，由于Rh阴性组中早期肿瘤和无法治愈的肿瘤较多，两组之间的预后是否不同尚不清楚。所有同时性癌患者均为Rh阳性。需要对血型抗原进行进一步研究，以阐明这些抗原与结直肠癌之间的关系。
