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经颅磁刺激在癫痫中的临床应用。

Clinical application of TMS to epilepsy.

作者信息

Joo Eun Yeon

机构信息

Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

出版信息

J Epilepsy Res. 2012 Dec 30;2(2):25-8. doi: 10.14581/jer.12007. eCollection 2012 Dec.

DOI:10.14581/jer.12007
PMID:24649458
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3952325/
Abstract

The role of transcranial magnetic stimulation in epileptology is discussed in this article. Usefulness of TMS are discussed as a diagnostic tool in testing altered cortical excitability in patients with epilepsy and the modes of action of antiepileptic drugs, which are helpful to evaluate the pathophysiology of epilepsy. Also potential therapeutic tool in epilepsy with repetitive transcranial magnetic stimulation would be mentioned.

摘要

本文讨论了经颅磁刺激在癫痫学中的作用。文中探讨了经颅磁刺激作为一种诊断工具在检测癫痫患者皮质兴奋性改变以及抗癫痫药物作用模式方面的实用性，这有助于评估癫痫的病理生理学。此外，还将提及重复经颅磁刺激在癫痫治疗中的潜在作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5282/3952325/7aea6ab59d1f/er-2-2-25-1f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5282/3952325/7aea6ab59d1f/er-2-2-25-1f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5282/3952325/7aea6ab59d1f/er-2-2-25-1f1.jpg

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本文引用的文献

1
Zonisamide changes unilateral cortical excitability in focal epilepsy patients.唑尼沙胺改变局灶性癫痫患者单侧皮质兴奋性。
J Clin Neurol. 2010 Dec;6(4):189-95. doi: 10.3988/jcn.2010.6.4.189. Epub 2010 Dec 31.
2
Zonisamide decreases cortical excitability in patients with idiopathic generalized epilepsy.唑尼沙胺可降低特发性全身性癫痫患者的皮质兴奋性。
Clin Neurophysiol. 2008 Jun;119(6):1385-92. doi: 10.1016/j.clinph.2008.02.008. Epub 2008 Apr 8.
3
Antiepileptic effects of low-frequency repetitive transcranial magnetic stimulation by different stimulation durations and locations.
不同刺激时长和部位的低频重复经颅磁刺激的抗癫痫作用
Clin Neurophysiol. 2007 Mar;118(3):702-8. doi: 10.1016/j.clinph.2006.11.008. Epub 2007 Jan 16.
4
Transcranial magnetic stimulation for the treatment of seizures: a controlled study.经颅磁刺激治疗癫痫：一项对照研究。
Neurology. 2002 Aug 27;59(4):560-2. doi: 10.1212/wnl.59.4.560.
5
Motor cortex excitability following short trains of repetitive magnetic stimuli.短串重复磁刺激后的运动皮层兴奋性
Exp Brain Res. 2001 Oct;140(4):453-9. doi: 10.1007/s002210100843.
6
Decreased susceptibility to pentylenetetrazol-induced seizures after low-frequency transcranial magnetic stimulation in rats.
Neurosci Lett. 2001 Sep 14;310(2-3):153-6. doi: 10.1016/s0304-3940(01)02116-4.
7
Therapeutic application of repetitive transcranial magnetic stimulation: a review.重复经颅磁刺激的治疗应用：综述
Clin Neurophysiol. 2001 Aug;112(8):1367-77. doi: 10.1016/s1388-2457(01)00585-5.
8
The mechanisms of action of commonly used antiepileptic drugs.常用抗癫痫药物的作用机制。
Pharmacol Ther. 2001 Apr;90(1):21-34. doi: 10.1016/s0163-7258(01)00122-x.
9
Studies of human motor physiology with transcranial magnetic stimulation.经颅磁刺激在人体运动生理学方面的研究。
Muscle Nerve Suppl. 2000;9:S26-32. doi: 10.1002/1097-4598(2000)999:9<::aid-mus6>3.0.co;2-i.
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Subthreshold 5-Hz repetitive transcranial magnetic stimulation of the human primary motor cortex reduces intracortical paired-pulse inhibition.对人类初级运动皮层进行阈下5赫兹重复经颅磁刺激可降低皮质内配对脉冲抑制。
Neurosci Lett. 2000 Dec 15;296(1):21-4. doi: 10.1016/s0304-3940(00)01616-5.