Kandala Ngianga-Bakwin, Mandungu Tumwaka P, Mbela Kisumbula, Nzita Kikhela P D, Kalambayi Banza B, Kayembe Kalambayi P, Emina Jacques B O
Division of Health Sciences, Populations, Evidence and Technologies Group, Medical School Building, The University of Warwick, Warwick Medical School, Coventry CV4 7AL, UK.
BMC Public Health. 2014 Mar 20;14:266. doi: 10.1186/1471-2458-14-266.
The child mortality rate is a good indicator of development. High levels of infectious diseases and high child mortality make the Democratic Republic of Congo (DRC) one of the most challenging environments for health development in Sub-Saharan Africa (SSA). Recent conflicts in the eastern part of the country and bad governance have compounded the problem. This study aimed to examine province-level geographic variation in under-five mortality (U5M), accounting for individual- and household-level risk factors including environmental factors such as conflict.
Our analysis used the nationally representative cross-sectional household sample of 8,992 children under five in the 2007 DRC Demographic and Health Survey. In the survey year, 1,005 deaths among this group were observed. Information on U5M was aggregated to the 11 provinces, and a Bayesian geo-additive discrete-time survival mixed model was used to map the geographic distribution of under-five mortality rates (U5MRs) at the province level, accounting for observable and unobservable risk factors.
The overall U5MR was 159 per 1,000 live births. Significant associations with risk of U5M were found for <24 month birth interval [posterior odds ratio and 95% credible region: 1.14 (1.04, 1.26)], home birth [1.13 (1.01, 1.27)] and living with a single mother [1.16 (1.03, 1.33)]. Striking variation was also noted in the risk of U5M by province of residence, with the highest risk in Kasaï-Oriental, a non-conflict area of the DRC, and the lowest in the conflict area of North Kivu.
This study reveals clear geographic patterns in rates of U5M in the DRC and shows the potential role of individual child, household and environmental factors, which are unexplained by the ongoing conflict. The displacement of mothers to safer areas may explain the lower U5MR observed at the epicentre of the conflict in North Kivu, compared with rates in conflict-free areas. Overall, the U5M maps point to a lack of progress towards the Millennium Development Goal of reducing U5M by half by 2015.
儿童死亡率是发展状况的一个良好指标。传染病高发和儿童死亡率高使得刚果民主共和国(DRC)成为撒哈拉以南非洲(SSA)健康发展最具挑战性的环境之一。该国东部近期的冲突以及治理不善使问题更加复杂。本研究旨在考察五岁以下儿童死亡率(U5M)的省级地理差异,同时考虑个体和家庭层面的风险因素,包括冲突等环境因素。
我们的分析使用了2007年刚果民主共和国人口与健康调查中具有全国代表性的8992名五岁以下儿童的横断面家庭样本。在调查年份,该组中有1005例死亡。五岁以下儿童死亡率信息汇总到11个省份,并使用贝叶斯地理加性离散时间生存混合模型来绘制省级五岁以下儿童死亡率(U5MRs)的地理分布,同时考虑可观察和不可观察的风险因素。
总体五岁以下儿童死亡率为每1000例活产159例。发现与五岁以下儿童死亡风险存在显著关联的因素有:出生间隔<24个月[后验比值比和95%可信区间:1.14(1.04,1.26)]、在家分娩[1.13(1.01,1.27)]以及与单身母亲生活在一起[1.16(1.03,1.33)]。居住省份的五岁以下儿童死亡风险也存在显著差异,刚果民主共和国非冲突地区的东方省风险最高,北基伍冲突地区风险最低。
本研究揭示了刚果民主共和国五岁以下儿童死亡率的明显地理模式,并显示了个体儿童、家庭和环境因素的潜在作用,而这些因素无法用当前冲突来解释。母亲向更安全地区的迁移可能解释了与无冲突地区相比,北基伍冲突中心地区观察到的较低五岁以下儿童死亡率。总体而言,五岁以下儿童死亡率地图表明在实现到2015年将五岁以下儿童死亡率减半的千年发展目标方面缺乏进展。