Wang Huan, Sun Xicai, Liu Quan, Wang Jingjing, Wang Dehui
Department of Otorhinolaryngology, Eye Ear Nose and Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Eur Arch Otorhinolaryngol. 2014 Nov;271(11):2975-82. doi: 10.1007/s00405-014-2972-z. Epub 2014 Mar 21.
A retrospective analysis of 31 lesions undergoing endoscopic surgery between 2006 and 2012 was undertaken. The data of patients' demographics, clinical features, operative parameters, follow-up period, and treatment outcomes were collected. A total of 31 patients were reviewed and consisted of 19 females and 12 males. The median age was 23 years (range 6-55). The surgical strategy included the exclusive endoscopic approach in 26 cases, endoscopic approach with external approach in 5 cases. Twenty-two cases were achieved completely resection and nine cases were subtotally resected. During the follow-up period (median: 25 months, range 4-80 months), 4 cases developed recurrences and there was no evidence of recurrence in the additional 27 cases included 8 cases living with no progressively growing residual tumor and 19 cases living without diseases. Our experience indicates that the endoscopic approach to manage ossifying fibroma of the nose and paranasal sinuses is safe and effective. However, more cases and a longer period of follow-up are required to define its long-term therapeutic effect.
对2006年至2012年间接受内镜手术的31个病变进行了回顾性分析。收集了患者的人口统计学数据、临床特征、手术参数、随访期和治疗结果。共对31例患者进行了评估，其中女性19例，男性12例。年龄中位数为23岁（范围6 - 55岁）。手术策略包括26例单纯内镜手术，5例内镜联合外入路手术。22例实现了完全切除，9例次全切除。在随访期（中位数：25个月，范围4 - 80个月）内，4例复发，其余27例无复发证据，其中8例无残余肿瘤进展存活，19例无疾病存活。我们的经验表明，内镜治疗鼻及鼻窦骨化性纤维瘤是安全有效的。然而，需要更多病例和更长随访期来确定其长期治疗效果。
