中国武汉液基薄层细胞学检测中所见的妇科感染

Gynecologic infections seen in ThinPrep cytological test in Wuhan, China.

作者信息

Zhou Hang, Jia Yao, Shen Jian, Wang Shaoshuai, Li Xiong, Yang Ru, Huang Kecheng, Hu Ting, Tang Fangxu, Zhou Jin, Yuan Jingping, Huang Lei, Tian Xun, Chen Zhilan, Zhang Qinghua, Wang Changyu, Xi Ling, Deng Dongrui, Wang Hui, Ma Ding, Li Shuang

机构信息

Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

出版信息

Front Med. 2014 Jun;8(2):236-40. doi: 10.1007/s11684-014-0322-6. Epub 2014 Mar 20.

DOI:10.1007/s11684-014-0322-6

PMID:24652121

Abstract

This study aimed to analyze the prevalence of bacterial, Candida, Trichomonas, and human papillomavirus (HPV) infections in ThinPrep cytological test (TCT) performed on women of Wuhan, China. ThinPrep smears were screened by two independent experienced pathologists and reported from 2008 to 2010. A total of 46 866 ThinPrep smears were studied, and smears with inflammation were analyzed. Of the 44 162 enrolled patients, inflammation changes were observed in 21 935 (49.7%) and specific infections in 6884 (31.4%). The infections detected were as follows: bacteria, 5663 (82.3%); Candida, 825 (12.0%); Trichomonas, 273 (4.0%); and HPV, 148 (2.1%). Significant changes were found in the prevalence of bacteria and Candida among women who underwent TCT before and after 2010. χ(2) revealed an increasing proportion of specific infections found in smears after 2010 (P = 0.000). In conclusion, bacterial infection was the most detectable in the ThinPrep smears, followed by Candida and Trichomonas. The prevalence of infection identified by TCT was found to be similar in previous literature in China.

摘要

本研究旨在分析在中国武汉女性中进行的液基薄层细胞学检测（TCT）中细菌、念珠菌、滴虫和人乳头瘤病毒（HPV）感染的患病率。液基薄层涂片由两位经验丰富的独立病理学家进行筛查，并报告了2008年至2010年的数据。共研究了46866份液基薄层涂片，并对有炎症的涂片进行了分析。在44162名纳入研究的患者中，观察到21935例（49.7%）有炎症变化，6884例（31.4%）有特定感染。检测到的感染情况如下：细菌感染5663例（82.3%）；念珠菌感染825例（12.0%）；滴虫感染273例（4.0%）；HPV感染148例（2.1%）。2010年前后接受TCT检查的女性中，细菌和念珠菌的患病率有显著变化。χ(2)检验显示2010年后涂片中发现的特定感染比例有所增加（P = 0.000）。总之，液基薄层涂片中最易检测到的感染是细菌感染，其次是念珠菌和滴虫感染。TCT检测出的感染患病率与中国以往文献报道相似。