van den Bos Doesjka, Zomer Sitaya, Kubat Bela
Faculty of Medicine, Leiden University, Hippocratespad 21, 2333 ZD, Leiden, The Netherlands.
Int J Legal Med. 2014 Jul;128(4):631-40. doi: 10.1007/s00414-014-0985-1. Epub 2014 Mar 21.
The age estimation of injuries, e.g., subdural hematomas (SDH), can play an important role in medicolegal cases. Various forensic textbooks provide tables of histomorphological changes in SDH in time. The analysis of these data showed that these tables employed different time intervals, although they were all based on only a single publication with a limited number of cases in some of the time periods. The present study aimed to add cases to the original article and to standardize the dating system of SDH. Results from two well-documented studies and 64 additional cases were analyzed, and the use of a number of immunohistochemical staining methods, which could support the histomorphological analysis of some of the changes, was proposed. The results showed that correct age estimation was achieved in approximately 95 % of the cases. Based on the cumulative data from the two published studies and the analysis of the additional cases, a simplified timing table was developed, and the potential pitfalls were addressed. This study shows that accurate age estimation of SDH is possible, provided that the rules established by this study are observed.
损伤（如硬膜下血肿，SDH）的年龄估计在法医学案件中可发挥重要作用。各种法医学教科书及时提供了SDH的组织形态学变化表格。对这些数据的分析表明，尽管这些表格都仅基于某一篇出版物，且某些时间段内的病例数量有限，但它们采用了不同的时间间隔。本研究旨在增加原始文章中的病例数量，并规范SDH的时间判定系统。分析了两项记录完善的研究结果以及另外64例病例，并提出使用一些免疫组织化学染色方法，这些方法可辅助某些变化的组织形态学分析。结果表明，约95%的病例实现了正确的年龄估计。基于两项已发表研究的累积数据以及对额外病例的分析，制定了一个简化的时间表，并阐述了潜在的陷阱。本研究表明，只要遵循本研究制定的规则，就有可能准确估计SDH的年龄。
