性发育遗传学：鱼类的进化乐园。
Genetics of sexual development: an evolutionary playground for fish.
机构信息
Zoological Institute, University of Basel, 4051 Basel, Switzerland.
出版信息
Genetics. 2014 Mar;196(3):579-91. doi: 10.1534/genetics.114.161158.
Abstract
Teleost fishes are the most species-rich clade of vertebrates and feature an overwhelming diversity of sex-determining mechanisms, classically grouped into environmental and genetic systems. Here, we review the recent findings in the field of sex determination in fish. In the past few years, several new master regulators of sex determination and other factors involved in sexual development have been discovered in teleosts. These data point toward a greater genetic plasticity in generating the male and female sex than previously appreciated and implicate novel gene pathways in the initial regulation of the sexual fate. Overall, it seems that sex determination in fish does not resort to a single genetic cascade but is rather regulated along a continuum of environmental and heritable factors.
摘要
硬骨鱼类是脊椎动物中物种最丰富的类群，其性别决定机制具有压倒性的多样性，经典地分为环境和遗传系统。在这里，我们回顾了鱼类性别决定领域的最新发现。在过去的几年中，在硬骨鱼类中发现了几个新的性别决定主调控因子和其他参与性发育的因素。这些数据表明，在产生雄性和雌性性别方面，遗传可塑性比以前认识到的要大得多，并暗示了新的基因途径在性命运的初始调节中起作用。总的来说，鱼类的性别决定似乎不是依赖于单一的遗传级联，而是沿着环境和可遗传因素的连续体进行调节的。
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