• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Study on anti-atherosclerotic effect of Suxiao Jiuxin Pill and its mechanism.速效救心丸抗动脉粥样硬化作用及其机制研究
Afr J Tradit Complement Altern Med. 2013 Nov 2;11(1):97-102. eCollection 2014.
2
Effects of suxiao jiuxin pill (see test) on oxidative stress and inflammatory response in rats with experimental atherosclerosis.速效救心丸（见试验）对实验性动脉粥样硬化大鼠氧化应激和炎症反应的影响。
J Tradit Chin Med. 2011 Jun;31(2):107-11. doi: 10.1016/s0254-6272(11)60022-8.
3
Chinese herbal medicine suxiao jiuxin wan for angina pectoris.治疗心绞痛的中药速效救心丸。
Cochrane Database Syst Rev. 2008 Jan 23;2008(1):CD004473. doi: 10.1002/14651858.CD004473.pub2.
4
Efficacy of Suxiao Jiuxin Pill on Coronary Heart Disease: A Meta-Analysis of Randomized Controlled Trials.速效救心丸治疗冠心病的疗效：一项随机对照试验的Meta分析
Evid Based Complement Alternat Med. 2018 Mar 27;2018:9745804. doi: 10.1155/2018/9745804. eCollection 2018.
5
Serum proteomic analysis reveals the cardioprotective effects of Shexiang Baoxin Pill and Suxiao Jiuxin Pill in a rat model of acute myocardial infarction.血清蛋白质组学分析揭示了麝香保心丸和速效救心丸对急性心肌梗死大鼠模型的心脏保护作用。
J Ethnopharmacol. 2022 Jul 15;293:115279. doi: 10.1016/j.jep.2022.115279. Epub 2022 Apr 8.
6
Anti-atherosclerosis and cardio-protective effects of the Angong Niuhuang Pill on a high fat and vitamin D3 induced rodent model of atherosclerosis.安宫牛黄丸对高脂及维生素D3诱导的动脉粥样硬化啮齿动物模型的抗动脉粥样硬化和心脏保护作用
J Ethnopharmacol. 2017 Jan 4;195:118-126. doi: 10.1016/j.jep.2016.11.015. Epub 2016 Nov 20.
7
[Determination of the contents of Ca, Mg, Fe, Cu and Zn in suxiao jiuxin pill and the analysis of Ca/Mg and Cu/Zn values].[速效救心丸中钙、镁、铁、铜和锌含量的测定及钙/镁和铜/锌值的分析]
Guang Pu Xue Yu Guang Pu Fen Xi. 2002 Jun;22(3):478-9.
8
Evaluation of the efficacy and safety of Suxiao Jiuxin Pill in the treatment of stable angina: A randomized, double-blind, placebo-controlled, multi-center clinical trial.速效救心丸治疗稳定性心绞痛的疗效和安全性评价：一项随机、双盲、安慰剂对照、多中心临床试验。
J Ethnopharmacol. 2024 Jan 10;318(Pt A):116959. doi: 10.1016/j.jep.2023.116959. Epub 2023 Jul 23.
9
A UPLC-MS/MS coupled with GC-MS method for quantification of twenty-one chemical ingredients from Suxiao Jiuxin pill in multiple tissue of rat and its application to tissue distribution study.一种 UPLC-MS/MS 与 GC-MS 联用方法，用于定量测定大鼠多种组织中 21 种麝香救心丸化学成分，并将其应用于组织分布研究。
J Pharm Biomed Anal. 2025 Jan 1;252:116461. doi: 10.1016/j.jpba.2024.116461. Epub 2024 Sep 7.
10
Searching for synergistic calcium antagonists and novel therapeutic regimens for coronary heart disease therapy from a Traditional Chinese Medicine, Suxiao Jiuxin Pill.从中药速效救心丸中寻找协同的钙拮抗剂和新的冠心病治疗方案。
J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Aug 15;1092:220-227. doi: 10.1016/j.jchromb.2018.06.015. Epub 2018 Jun 8.

引用本文的文献

1
A Potential Therapeutic Effect of Suxiao Jiuxin Pills in Treating Postacute Sequelae of COVID-19: Case Report.速效救心丸治疗新型冠状病毒肺炎急性感染期后综合征的潜在疗效：病例报告
Case Rep Infect Dis. 2024 Nov 21;2024:4713552. doi: 10.1155/crdi/4713552. eCollection 2024.
2
A six-herb Chinese medicine composition ointment as a promising candidate for treatment of hypertrophic scars.一种由六种草药组成的中药组合物软膏有望成为治疗增生性瘢痕的候选药物。
Chin Herb Med. 2020 Dec 29;13(2):210-220. doi: 10.1016/j.chmed.2020.12.007. eCollection 2021 Apr.
3
Atheroprotective Effects and Mechanisms of Postmarketing Chinese Patent Formulas in Atherosclerosis Models: A Systematic Review.上市后中药复方制剂在动脉粥样硬化模型中的动脉粥样硬化保护作用及机制：一项系统评价
Evid Based Complement Alternat Med. 2021 Nov 27;2021:4010607. doi: 10.1155/2021/4010607. eCollection 2021.
4
Protective Mechanisms of Suxiao Jiuxin Pills () on Myocardial Ischemia-Reperfusion Injury in vivo and in vitro.麝香保心丸对心肌缺血再灌注损伤的体内外保护作用。
Chin J Integr Med. 2020 Aug;26(8):583-590. doi: 10.1007/s11655-020-2726-2. Epub 2020 Jun 10.
5
Influence of Orally Administered Borneol on the Expression of Hepatic Transporters in Rats.口服冰片对大鼠肝脏转运体表达的影响。
Eur J Drug Metab Pharmacokinet. 2019 Feb;44(1):103-109. doi: 10.1007/s13318-018-0499-1.
6
Efficacy of Suxiao Jiuxin Pill on Coronary Heart Disease: A Meta-Analysis of Randomized Controlled Trials.速效救心丸治疗冠心病的疗效：一项随机对照试验的Meta分析
Evid Based Complement Alternat Med. 2018 Mar 27;2018:9745804. doi: 10.1155/2018/9745804. eCollection 2018.
7
Suxiao Jiuxin Pill protects cardiomyocytes against mitochondrial injury and alters gene expression during ischemic injury.速效救心丸可保护心肌细胞免受线粒体损伤，并在缺血性损伤期间改变基因表达。
Exp Ther Med. 2017 Oct;14(4):3523-3532. doi: 10.3892/etm.2017.4964. Epub 2017 Aug 18.

本文引用的文献

1
Inflammation and atherosclerosis.炎症与动脉粥样硬化。
Circulation. 2002 Mar 5;105(9):1135-43. doi: 10.1161/hc0902.104353.
2
Identification and localization of the cytokine SDF1 and its receptor, CXC chemokine receptor 4, to regions of necrosis and angiogenesis in human glioblastoma.细胞因子基质细胞衍生因子1（SDF1）及其受体CXC趋化因子受体4（CXCR4）在人胶质母细胞瘤坏死和血管生成区域的鉴定与定位。
Clin Cancer Res. 2000 Jan;6(1):102-11.
3
Chemokine SDF-1 enhances circulating CD34(+) cell proliferation in synergy with cytokines: possible role in progenitor survival.趋化因子SDF-1与细胞因子协同作用可增强循环CD34(+)细胞的增殖：对祖细胞存活的可能作用。
Blood. 2000 Feb 1;95(3):756-68.
4
Atherosclerosis and the arterial smooth muscle cell: Proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis.动脉粥样硬化与动脉平滑肌细胞：平滑肌增殖是动脉粥样硬化病变发生过程中的关键事件。
Science. 1973 Jun 29;180(4093):1332-9. doi: 10.1126/science.180.4093.1332.

速效救心丸抗动脉粥样硬化作用及其机制研究

Study on anti-atherosclerotic effect of Suxiao Jiuxin Pill and its mechanism.

作者信息

Guo Qing-Xu, Zhang Jun, Li Yu-Qing, Zhang Gui-Fu

机构信息

The Military General Hospital of BeiJing PLASurgical Dept Vascular Diseases, Beijing, China.

出版信息

Afr J Tradit Complement Altern Med. 2013 Nov 2;11(1):97-102. eCollection 2014.

PMID:24653560
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3957248/
Abstract

BACKGROUND

Suxiao Jiuxin Pill is composed of Ligusticum wallichii, Borneolum Syntheticum and other drugs; it has qi promoting and blood circulation activating, meridian dredging and pain relieving efficacies. The objective of this paper is to study the effect of Suxiao Jiuxin Pill (quick-acting heart reliever), in atherosclerosis (AS) rat model and explore the mechanism for its prevention and treatment of AS.

MATERIALS AND METHODS

AS rat model was established by high cholesterol diet and single intra-peritoneal injection of increased dose of vitamin D3.

RESULTS

Compared with the model group, Suxiao Jiuxin Pill medium-and high-dose groups and atorvastatin group can effectively regulate lipid metabolism.

CONCLUSION

We conclude that Suxiao Jiuxin Pill has a good hypo-lipidemic effect, and can inhibit the occurrence and development of AS.

摘要

背景

速效救心丸由川芎、冰片等药物组成；具有行气活血、通络止痛之功效。本文旨在研究速效救心丸对动脉粥样硬化（AS）大鼠模型的作用，并探讨其防治AS的机制。

材料与方法

采用高胆固醇饮食并单次腹腔注射大剂量维生素D3建立AS大鼠模型。

结果

与模型组相比，速效救心丸中、高剂量组及阿托伐他汀组能有效调节脂质代谢。

结论

我们得出结论，速效救心丸具有良好的降血脂作用，并能抑制AS的发生和发展。