Xie Hui-chun, Han Hong-Ping, Chen Zhi, He Jian-Ping
The Key Laboratory of Education Ministry on Environments and Resources in Tibetan Plateau, Qinghai-Normal University, 38 West Wusi Road, Xining, 810008 ; Shaanxi Normal University, 199 South Chang'an Road, Xi'an, 710062.
The Key Laboratory of Education Ministry on Environments and Resources in Tibetan Plateau, Qinghai-Normal University, 38 West Wusi Road, Xining, 810008.
Afr J Tradit Complement Altern Med. 2013 Nov 2;11(1):209-12. eCollection 2014.
The content of resveratrol is relatively high in Polygonum cuspidatum Sieb. et Zucc., and the resveratrol has the effect of blood vessel dilating, microcirculation improving, platelet aggregation inhibiting and anti-cancer. The objective of this paper was to study the effect of resveratrol on lipid metabolism in hyperlipidemia mice.
Through the establishment of an experimental mouse model of hyperlipidemia, the effect of resveratrol on change in total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-c), and low-density lipoprotein cholesterol (LDL-c) levels in mouse serum were determined.
Resveratrol group can apparently reduce TC, TG, LDL-c and AI of hyperlipidemic mice in a dose effect manner.
We concluded that resveratrol can effectively reduce blood lipid levels of hyperlipidemic mice.
虎杖中白藜芦醇含量相对较高,白藜芦醇具有扩张血管、改善微循环、抑制血小板聚集及抗癌作用。本文旨在研究白藜芦醇对高脂血症小鼠脂质代谢的影响。
通过建立高脂血症实验小鼠模型,测定白藜芦醇对小鼠血清中总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-c)和低密度脂蛋白胆固醇(LDL-c)水平变化的影响。
白藜芦醇组能明显以剂量效应方式降低高脂血症小鼠的TC、TG、LDL-c及AI。
我们得出结论,白藜芦醇可有效降低高脂血症小鼠的血脂水平。