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纳米混悬液作为一种多功能载体型药物递送系统——综述

Nanosuspensions as a versatile carrier based drug delivery system--an overview.

作者信息

Sudhakar Beeravelli, NagaJyothi Kothagunda, Murthy K V Ramana

机构信息

Department of Pharmaceutical Technology, A.U. College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, Andhra Pradesh, India-530003.

出版信息

Curr Drug Deliv. 2014;11(3):299-305. doi: 10.2174/1567201811666140323131342.

DOI:10.2174/1567201811666140323131342
PMID:24655052
Abstract

Nanotechnology is being explored in many ways to design a new chemical entity (NCE) to an active pharmaceutical ingredient (API). Of the different nanotechnologies, Nanosuspensions has gained a lot of interest due to its ease of production and applicability to a large number of drugs. This present review article on nanosuspensions is focused on the various principles, production techniques, stability problems, various marketed formulations and current trends associated with the nanosuspensions.

摘要

人们正在从多个方面探索纳米技术,以将新化学实体(NCE)设计成活性药物成分(API)。在不同的纳米技术中,纳米混悬液因其易于生产且适用于大量药物而备受关注。这篇关于纳米混悬液的综述文章聚焦于纳米混悬液的各种原理、生产技术、稳定性问题、各种上市制剂以及当前趋势。

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