头颈部肉瘤：29 例分析。

Head and neck sarcoma: analysis of 29 cases.

机构信息

ENT department, Coimbra university hospitals, Praceta Mota Pinto, 3000 Coimbra, Portugal.

Pathology department, Oporto oncology institute, Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.

出版信息

Eur Ann Otorhinolaryngol Head Neck Dis. 2014 Apr;131(2):83-6. doi: 10.1016/j.anorl.2012.11.007. Epub 2014 Mar 18.

DOI:10.1016/j.anorl.2012.11.007

PMID:24656875

Abstract

OBJECTIVES

The purpose of this study was to analyze the outcome of patients suffering from head and neck sarcomas and to identify indicators of outcome.

MATERIAL AND METHODS

The medical records of 43 patients treated between 2000 and 2010 were analyzed. All patients were suffering from primary head and neck sarcoma. The final study sample included 29 patients.

RESULTS

Mean survival was 56 months. Overall 2- and 5-year survivorship was 69% and 31% respectively. Parameters positively influencing survival were: male gender; non-smoker; alcohol consumption; age <18 years; tumor size <5 cm; location (nasal pyramid, jaw and maxillary sinus). Rhabdomyosarcoma and synovial sarcoma were the histological forms positively influencing prognosis. Age was the only parameter significantly influencing survival (P<0.05).

CONCLUSIONS

The present overall 5-year survivorship was similar to the lower limit of the available literature data. Age was the only proven indicator of outcome. In order to have more reliable data it is essential to set up broader databases.

摘要