Zahran Eman, Risha Engy, Abdelhamid Fatma, Mahgoub Hebata Allah, Ibrahim Tarek
Department of Internal Medicine, Infections and Fish Diseases, Faculty of Veterinary Medicine, Mansoura University, Mansoura 35516, Egypt.
Clinical Pathology Department, Faculty of Veterinary Medicine, Mansoura University, Mansoura 35516, Egypt.
Fish Shellfish Immunol. 2014 May;38(1):149-57. doi: 10.1016/j.fsi.2014.03.002. Epub 2014 Mar 20.
This work investigated the potential immunomodulatory and growth-promoting effects of Astragalus polysaccharides (APS) in Nile tilapia (Oreochromis niloticus). The dietary supplementation with APS (1500 mg/kg of diet) caused a significant increase in growth parameters (initial and final weight, weight gain (WG), specific growth rate (SGR), feed conversion ratio (FCR) and feed intake (FI), when compared to non-supplemented control basal diet. In addition, APS upregulated the phagocytic activity, the respiratory burst activity, plasma lysozyme, the bactericidal activity, superoxide dismutase (SOD), glutathione peroxidase (GPx), and amylase activity. However, it had no effect on serum nitric oxide (NO) or Malondialdehyde (MDA) levels. While APS had no effect of intestinal histology, a slight increase in the villi length was recorded. Collectively, our results indicate that dietary APS supplementation could improve the growth performance and the immune parameters of cultured tilapia fish.
本研究调查了黄芪多糖（APS）对尼罗罗非鱼（Oreochromis niloticus）潜在的免疫调节和促生长作用。与未添加APS的对照基础日粮相比，日粮中添加APS（1500毫克/千克日粮）可显著提高生长参数（初始体重和终末体重、增重（WG）、特定生长率（SGR）、饲料转化率（FCR）和采食量（FI））。此外，APS上调了吞噬活性、呼吸爆发活性、血浆溶菌酶、杀菌活性、超氧化物歧化酶（SOD）、谷胱甘肽过氧化物酶（GPx）和淀粉酶活性。然而，它对血清一氧化氮（NO）或丙二醛（MDA）水平没有影响。虽然APS对肠道组织学没有影响，但记录到绒毛长度略有增加。总体而言，我们的结果表明，日粮中添加APS可以改善养殖罗非鱼的生长性能和免疫参数。
