Geyer M, Vasile M, Hermann W
Innere Medizin mit Schwerpunkt Rheumatologie, Justus-Liebig-Universität Gießen, Gießen, Deutschland,
Z Rheumatol. 2014 Mar;73(2):149-60; quiz 161-2. doi: 10.1007/s00393-013-1314-7.
Capillaroscopy is performed to evaluate the morphology, frequency and blood flow of nailfold capillaries as well as relevant extracapillary changes in rheumatic conditions. The main indication is the differentiation between primary and secondary Raynaud's phenomenon. Various rheumatic conditions show different and partially typical pathognomonic alterations of the microcirculation or capillary patterns. This simple, noninvasive, inexpensive and effective technique is well suited for early diagnosis, especially of connective tissue diseases. The specific significance is highest for systemic sclerosis which is the most frequently evaluated entity. The corresponding microscopic alterations allow stage-adapted conclusions concerning the acuity of inflammation to be formed. That is not the only reason why capillaroscopy represents an important tool in follow-up controls and together with other techniques, such as flow measurement by laser Doppler, further conclusions can be drawn.
进行甲襞毛细血管镜检查以评估甲襞毛细血管的形态、频率和血流以及风湿性疾病中相关的毛细血管外变化。主要适应证是原发性和继发性雷诺现象的鉴别。各种风湿性疾病表现出不同的、部分典型的微循环或毛细血管模式的特征性改变。这种简单、无创、廉价且有效的技术非常适合早期诊断,尤其是结缔组织疾病。对于系统性硬化症(最常评估的疾病实体),其特异性意义最高。相应的微观改变有助于形成关于炎症严重程度的分期适应性结论。这并不是甲襞毛细血管镜检查成为随访监测重要工具的唯一原因,并且与其他技术(如激光多普勒血流测量)一起,可以得出进一步的结论。