Markovic-Denic Ljiljana, Cirkovic Andia, Zivkovic Snezana, Stanic Danica, Skodric-Trifunovic Vesna
University of Belgrade, Faculty of Medicine, Institute of Epidemiology, Belgrade, Serbia.
J BUON. 2014 Jan-Mar;19(1):273-7.
Cancer is the one of the leading cause of death worldwide. The aim of this study was to examine cancer mortality trends in the population of central Serbia in the period from 2002 to 2011.
The descriptive epidemiological method was used. The mortality from all malignant tumors (code C00-C96 of the International Disease Classification) was registered. The source of mortality data was the published material of the Cancer Registry of Serbia. The source of population data was the census of 2002 and 2011 and the estimates for inter-census years. Non-standardized, age-adjusted and age-specific mortality rates were calculated. Age adjustment of mortality rates was performed by the direct method of standardization. Trend lines were estimated using linear regression.
During 2002-2011, cancer caused about 20% of all deaths each year in central Serbia. More men (56.9%) than women (43.1%) died of cancer. The average mortality rate for men was 1.3 times higher compared to women. A significant trend of increase of the age-adjusted mortality rates was recorded both for males (p<0.001) and for females (p=0.02). Except gastric cancer, the age-adjusted mortality rates in men were significantly increased for lung cancer (p=0.02), colorectal cancer (p<0.05), prostate cancer (p=0.01) and pancreatic cancer (p=0.01). Age-adjusted mortality rates for breast cancer in females were remarkably increased (p=0.01), especially after 2007.
In central Serbia during the period from 2002 to 2011, there was an increasing trend in mortality rates due to cancers in both sexes. Cancer mortality in males was 1.3-fold higher compared to females.
癌症是全球主要死因之一。本研究旨在考察2002年至2011年期间塞尔维亚中部人口的癌症死亡率趋势。
采用描述性流行病学方法。记录所有恶性肿瘤（国际疾病分类代码C00 - C96）的死亡率。死亡率数据来源为塞尔维亚癌症登记处的已发表资料。人口数据来源为2002年和2011年的人口普查以及两次普查年份之间的估计数据。计算了非标准化、年龄调整和年龄别死亡率。死亡率的年龄调整采用直接标准化法。使用线性回归估计趋势线。
2002 - 2011年期间，癌症每年导致塞尔维亚中部约20%的死亡。死于癌症的男性（56.9%）多于女性（43.1%）。男性的平均死亡率比女性高1.3倍。男性和女性的年龄调整死亡率均呈现显著上升趋势（男性p<0.001，女性p = 0.02）。除胃癌外，男性肺癌（p = 0.02）、结直肠癌（p<0.05）、前列腺癌（p = 0.01）和胰腺癌（p = 0.01）的年龄调整死亡率显著上升。女性乳腺癌的年龄调整死亡率显著上升（p = 0.01），尤其是在2007年之后。
2002年至2011年期间，塞尔维亚中部男女因癌症导致的死亡率均呈上升趋势。男性癌症死亡率比女性高1.3倍。
