Schoel J, Smolle J, Kerl H
Hautklinik Universität Heidelberg.
Hautarzt. 1989 Jan;40(1):34-6.
Prostatic carcinoma accounts for about 1% of all cancers that metastasize to the skin. The regions most frequently involved are the genital region, the head and the trunk. Clinically the lesions present as nodules; less often diffuse infiltrates, red macules and papules or tumors of an angiomatous appearance occur. Histopathological examination of skin biopsy specimens can reveal gland-like, epithelial or anaplastic differentiation of tumor cells. Prostatic origin can be proven by the immunohistological demonstration of acid prostatic phosphatase or prostatic specific antigen in paraffin-embedded specimens taken for routine histological examination.
前列腺癌约占所有皮肤转移癌的1%。最常受累的部位是生殖器区域、头部和躯干。临床上，病变表现为结节；较少见的是弥漫性浸润、红色斑疹和丘疹或血管瘤样外观的肿瘤。皮肤活检标本的组织病理学检查可显示肿瘤细胞的腺样、上皮样或间变分化。通过在常规组织学检查获取的石蜡包埋标本中免疫组织化学显示酸性前列腺磷酸酶或前列腺特异性抗原，可证实前列腺来源。
