Piqué Duran E, Paradela A, Fariña M C, Escalonilla P, Soriano M L, Olivares M, Sarasa J L, Martín L, Requena L
Department of Dermatology, Fundación Jiménez Díaz, Madrid, Spain.
J Surg Oncol. 1996 Jun;62(2):144-7. doi: 10.1002/(SICI)1096-9098(199606)62:2<144::AID-JSO12>3.0.CO;2-8.
Cutaneous metastasis from carcinoma of the prostate is a rare phenomenon. When it occurs, metastases usually appear as multiple nodules involving the suprapubic area and the anterior aspect of the thighs. We report on two cases of cutaneous metastases from prostatic carcinoma, one of them presenting the stereotypical clinical and histopathological findings, whereas in the other one cutaneous metastasis consisted of a morphea-like plaque on the chest. Histopathologically, the later case revealed accumulations of neoplastic cells distributed in a folliculotropic pattern. In both examples immunohistochemical study with prostatic specific antigen (PSA) confirmed the prostatic origin of the metastases. We review the literature on this subject.
前列腺癌的皮肤转移是一种罕见现象。当发生时，转移灶通常表现为涉及耻骨上区域和大腿前部的多个结节。我们报告了两例前列腺癌皮肤转移病例，其中一例呈现典型的临床和组织病理学表现，而另一例皮肤转移表现为胸部的硬斑病样斑块。组织病理学上，后一例显示肿瘤细胞呈毛囊趋向性分布。在这两个病例中，前列腺特异性抗原（PSA）免疫组化研究证实了转移灶的前列腺来源。我们回顾了关于该主题的文献。
