Int J Oral Maxillofac Implants. 2014;29 Suppl:292-307. doi: 10.11607/jomi.2014suppl.g5.1.
To systematically appraise whether anti-infective protocols are effective in preventing biologic implant complications and implant loss after a mean observation period ≥ 10 years after loading.
An electronic search of Medline via PubMed and Embase via Ovid databases complemented by manual search was conducted up to October 31, 2012. Studies were included provided that they were published in English, German, French, or Italian, and conducted on ≥ 20 partially and fully edentulous patients with dental implants and regular (≥ 1×/year) supportive periodontal therapy (SPT) over a mean observation period ≥ 10 years. Assessment of the identified studies and data extraction were performed independently by two reviewers. Authors were contacted if required. Collected data were reported by descriptive methods.
The initial electronic search resulted in the identification of 994 titles from Medline via PubMed and 531 titles from Embase via Ovid databases, respectively. After elimination of duplicate titles and exclusion of 60 full-text articles, 143 articles were analyzed, resulting in 15 studies eligible for qualitative analysis. The implant survival rate ranged from 85.7% to 99.2% after a mean observation period ≥ 10 years. One comparative study assessed the effects of regular SPT on the occurrence of biologic complications and implant loss. Overall, regular diagnosis and implementation of anti-infective therapeutic protocols were effective in the management of biological complications and prevention of implant loss. Residual probing depths at the end of active periodontal therapy and development of reinfection during supportive periodontal therapy (SPT) represented a significant risk for the onset of peri-implantitis and implant loss. Comparative studies indicated that implant survival and success rates were lower in periodontally compromised vs noncompromised patients.
In order to achieve high long-term survival and success rates of dental implants and their restorations, enrollment in regular SPT including anti-infective preventive measures should be implemented. Therapy of peri-implant mucositis should be considered as a preventive measure for the onset of peri-implantitis. Completion of active periodontal therapy should precede implant placement in periodontally compromised patients.
系统评价抗感染方案是否能有效预防生物植入物并发症，并在加载后 10 年以上的平均观察期内预防植入物丢失。
通过 PubMed 中的 Medline 和 Ovid 中的 Embase 进行电子搜索，并辅以手动搜索，截至 2012 年 10 月 31 日。如果研究发表在英语、德语、法语或意大利语中，并对 20 名以上部分或完全无牙的患者进行了研究，这些患者接受了牙科植入物和定期（≥ 1 次/年）支持性牙周治疗（SPT），平均观察期≥10 年，则将这些研究纳入研究。由两位评审员独立进行研究评估和数据提取。如果需要，与作者联系。收集的数据通过描述性方法报告。
最初的电子搜索从 Medline 中的 PubMed 和 Embase 中的 Ovid 数据库中分别获得了 994 个和 531 个标题。在消除重复标题并排除 60 篇全文文章后，分析了 143 篇文章，其中 15 篇文章符合定性分析的标准。在平均观察期≥10 年后，植入物的存活率从 85.7%到 99.2%不等。一项比较研究评估了定期 SPT 对生物并发症和植入物丢失发生的影响。总体而言，定期诊断和实施抗感染治疗方案在管理生物并发症和预防植入物丢失方面是有效的。主动牙周治疗结束时的剩余探诊深度和支持性牙周治疗（SPT）期间的再感染是发生种植体周围炎和植入物丢失的显著风险因素。比较研究表明，在牙周受损和非受损患者中，植入物的存活率和成功率较低。
为了实现牙科植入物及其修复体的高长期存活率和成功率，应实施包括抗感染预防措施在内的定期 SPT。治疗种植体周围黏膜炎应被视为预防种植体周围炎发生的一种措施。在牙周受损患者中，应在植入物放置前完成主动牙周治疗。
