Kato Mamoru, He Yu-Min, Dibwe Dya Fta, Li Feng, Awale Suresh, Kadota Shigetoshi, Tezuka Yasuhiro
Nat Prod Commun. 2014 Jan;9(1):1-2.
From a MeOH extract of powdered roots of Wikstroemia indica, we isolated a new guaian-type sesquiterpene (1) and two known guaian-type sesquiterpenes [oleodaphnal (2), 1alpha,7alpha,10alphaH-guaia-4,11-dien-3-one (3)], together with twelve known compounds: (+)-arctigenin, (+)-matairesinol, (+)-trachelogenin, (+)-nortrachelogenin, (+)-hinokinin, (+)-kusunokinin, 7-methoxycoumarin, 7-hydroxycoumarin (umbelliferone), daphnogitin, daphnoretin, salicifoliol, and (-)-pinoresinol. The structure of compound 1 was determined to be 4,10,11-guaiatrien-3-one-14-oic acid, by the analyses of spectral data.
从了哥王的根粉甲醇提取物中,我们分离出一种新的愈创木烷型倍半萜(1)和两种已知的愈创木烷型倍半萜[油地奥酚(2),1α,7α,10αH-愈创木-4,11-二烯-3-酮(3)],以及十二种已知化合物:(+)-牛蒡子苷元、(+)-罗汉松脂素、(+)-桂皮树脂醇、(+)-去甲桂皮树脂醇、(+)-日桧素、(+)-草苁蓉内酯、7-甲氧基香豆素、7-羟基香豆素(伞形花内酯)、瑞香毒素、瑞香素、柳叶木兰脂素和(-)-松脂醇。通过光谱数据分析,确定化合物1的结构为4,10,11-愈创木三烯-3-酮-14-酸。