J Tradit Chin Med. 2013 Oct;33(5):592-6. doi: 10.1016/s0254-6272(14)60026-1.
To observe the influence of moxibustion temperature on blood lipids, endothelin-1 (ET-1), nitric oxide (NO), and ET-1/NO in hyperlipidemia patients.
Forty-two primary hyperlipidemia patients were randomly divided into two groups of 21 and treated with moxibustion at different temperatures. Moxibustion was performed with the moxa roll 2.5-3.0 cm from the skin in the treatment group and 4 cm in the control group, 10 min per point, once every other day. Skin temperature was precisely measured with a thermometer during moxibustion. After a 12-week treatment, seven measurements of blood lipids, ET-1, and NO were recorded.
Total cholesterol and triglyceride, were lower in the treatment group than in the control group (P < 0.05). Serum ET-1 and ET-1/NO was obviously lowered in the treatment group (P < 0.001). Moxibustion regulated NO and ET-1/NO in the treatment group much better than in the control group.
Moxibustion can regulate blood lipids and clear blood vessels. Moxibustion at 45 degrees C has a better effect than moxibustion at 38 degrees C on regulating blood lipids and protecting vascular endothelial function, indicating that suitable temperature influences the curative effect of moxibustion.
观察艾灸温度对高血脂患者血脂、内皮素-1（ET-1）、一氧化氮（NO）及 ET-1/NO 的影响。
将 42 例原发性高血脂患者随机分为两组，每组 21 例。治疗组艾灸距离皮肤 2.5-3.0cm，对照组 4cm，每点 10min，隔日 1 次。艾灸时用温度计精确测量皮肤温度。治疗 12 周后，记录血脂、ET-1 和 NO 的 7 项测量值。
治疗组总胆固醇和甘油三酯均低于对照组（P<0.05）。治疗组血清 ET-1 和 ET-1/NO 明显降低（P<0.001）。艾灸组对 NO 和 ET-1/NO 的调节明显优于对照组。
艾灸可调节血脂，清除血管。45°C 艾灸比 38°C 艾灸在调节血脂和保护血管内皮功能方面效果更好，表明适宜的温度影响艾灸的疗效。
