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人类胎盘项目:实时观察胎盘的结构、发育及功能。

The Human Placenta Project: placental structure, development, and function in real time.

作者信息

Guttmacher A E, Maddox Y T, Spong C Y

机构信息

Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, United States.

Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, United States.

出版信息

Placenta. 2014 May;35(5):303-4. doi: 10.1016/j.placenta.2014.02.012. Epub 2014 Mar 6.

Abstract

Despite its crucial role in the health of both the fetus and the pregnant woman, the placenta is the least understood human organ. Since a growing body of evidence also underscores the importance of placental development in the lifelong health of both mother and offspring, this lack of knowledge about placental structure and function is particularly concerning. Given modern approaches and technologies and the ability to develop new methods, we propose a coordinated "Human Placenta Project", with the ultimate goal of understanding human placental structure, development, and function in real time.

摘要

尽管胎盘在胎儿和孕妇的健康中起着至关重要的作用,但它却是人类了解最少的器官。越来越多的证据也强调了胎盘发育对母亲和后代终身健康的重要性,因此,对胎盘结构和功能的这种认知不足尤其令人担忧。鉴于现代方法和技术以及开发新方法的能力,我们提议开展一个协调一致的“人类胎盘项目”,其最终目标是实时了解人类胎盘的结构、发育和功能。

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本文引用的文献

1
Linking intrauterine growth restriction and blood pressure: insight into the human origins of cardiovascular disease.
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4
Reversal of gene dysregulation in cultured cytotrophoblasts reveals possible causes of preeclampsia.
J Clin Invest. 2013 Jul;123(7):2862-72. doi: 10.1172/JCI66966. Epub 2013 Jun 24.
5
Importance of engaging obstetrician/gynecologists in cardiovascular disease prevention.
Curr Opin Cardiol. 2013 Sep;28(5):547-53. doi: 10.1097/HCO.0b013e328364298e.
6
Placental programming of chronic diseases, cancer and lifespan: a review.
Placenta. 2013 Oct;34(10):841-5. doi: 10.1016/j.placenta.2013.07.063. Epub 2013 Aug 2.
7
Fetomaternal immune cross-talk and its consequences for maternal and offspring's health.
Nat Med. 2013 May;19(5):548-56. doi: 10.1038/nm.3160. Epub 2013 May 7.
8
The placenta in toxicology. Part II: Systemic and local immune adaptations in pregnancy.
Toxicol Pathol. 2014;42(2):327-38. doi: 10.1177/0192623313482205. Epub 2013 Mar 26.
9
From mice to women: the conundrum of immunity to infection during pregnancy.
J Reprod Immunol. 2013 Mar;97(1):62-73. doi: 10.1016/j.jri.2012.10.015.
10
Maternal/fetal determinants of insulin resistance in women during pregnancy and in offspring over life.
Curr Diab Rep. 2013 Apr;13(2):238-44. doi: 10.1007/s11892-012-0360-x.

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