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[预防术后粘连的实验研究]

[Experimental studies of the prevention of postoperative adhesions].

作者信息

Schwarz J, Donat H

机构信息

Klinik für Gynäkologie und Geburtshilfe, Medizinischen Akademie Magdeburg.

出版信息

Zentralbl Gynakol. 1989;111(2):110-8.

PMID:2466384
Abstract

Female wistar rats were used for the testing of different substances to prevent postoperative intraabdominal adhesions. It could be demonstrated that the best results were obtained by dextran 70 with a concentration of 10%. Good effects were seen also by contrykal (aprotinin) and hylase (hyaluronidase). By the combination of dextran 70 30% with contrykal the spread of adhesions was very low but the effect was not significant better than with dextran 70 10% alone. For the prevention of intraabdominal adhesions operative techniques with minimal lesions are important too of the peritoneal epithelium.

摘要

使用雌性Wistar大鼠来测试不同物质预防术后腹腔内粘连的效果。结果表明,浓度为10%的右旋糖酐70效果最佳。抑肽酶和透明质酸酶也有良好效果。30%的右旋糖酐70与抑肽酶联合使用时,粘连扩散程度很低,但效果并不比单独使用10%的右旋糖酐70显著更好。对于预防腹腔内粘连,对腹膜上皮损伤最小的手术技术也很重要。

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