Schwarz J, Donat H
Klinik für Gynäkologie und Geburtshilfe, Medizinischen Akademie Magdeburg.
Zentralbl Gynakol. 1989;111(2):110-8.
Female wistar rats were used for the testing of different substances to prevent postoperative intraabdominal adhesions. It could be demonstrated that the best results were obtained by dextran 70 with a concentration of 10%. Good effects were seen also by contrykal (aprotinin) and hylase (hyaluronidase). By the combination of dextran 70 30% with contrykal the spread of adhesions was very low but the effect was not significant better than with dextran 70 10% alone. For the prevention of intraabdominal adhesions operative techniques with minimal lesions are important too of the peritoneal epithelium.
使用雌性Wistar大鼠来测试不同物质预防术后腹腔内粘连的效果。结果表明,浓度为10%的右旋糖酐70效果最佳。抑肽酶和透明质酸酶也有良好效果。30%的右旋糖酐70与抑肽酶联合使用时,粘连扩散程度很低,但效果并不比单独使用10%的右旋糖酐70显著更好。对于预防腹腔内粘连,对腹膜上皮损伤最小的手术技术也很重要。