Kawai Y, Takagi H
1st Department of Anatomy, Osaka City University Medical School, Japan.
Brain Res. 1989 Feb 13;479(2):344-8. doi: 10.1016/0006-8993(89)91638-7.
Synaptic interaction between parvicellular adrenergic neurons and substance P (SP) afferents in the caudal part of the nucleus of the tractus solitarius (NTS) was demonstrated by the immunoelectron microscopic mirror method, using antisera against phenylethanolamine N-methyltransferase (PNMT) and SP. SP-immunoreactive (SP-IR) terminals formed synaptic contacts with PNMT-IR neurons. It is suggested that SP afferents directly affect parvicellular adrenergic neurons via synapse in the NTS.
采用抗苯乙醇胺N-甲基转移酶(PNMT)和P物质(SP)的抗血清,通过免疫电子显微镜镜像法,证实了孤束核(NTS)尾部小细胞肾上腺素能神经元与SP传入纤维之间的突触相互作用。SP免疫反应性(SP-IR)终末与PNMT-IR神经元形成突触联系。提示SP传入纤维通过NTS中的突触直接影响小细胞肾上腺素能神经元。