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外阴红斑及灼痛：红斑性肢痛症的一种可能表型。

Erythema and burning pain in the vulva: a possible phenotype of erythromelalgia.

作者信息

Johnson Elisabeth, Iyer Priya, Eanes Alisa, Zolnoun Denniz

机构信息

Pelvic Pain Research Unit, Division of Advanced Laparoscopy and Pelvic Pain, Department of Obstetrics and Gynecology, School of Medicine, University of North Carolina, Chapel Hill, NC 27599-7570, USA.

出版信息

Case Rep Med. 2011;2011:374167. doi: 10.1155/2011/374167. Epub 2011 Apr 13.

DOI:10.1155/2011/374167
PMID:21541228
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3085391/
Abstract

We report a case of burning vulvar pain accompanied by erythema responding to an oral combination of a benzodiazepine and a beta blocker. The positive response to two medication classes used in the treatment of erythromelalgia supports the possibility of a localized manifestation of this disorder in the genital region.

摘要

我们报告一例伴有红斑的外阴灼痛病例，口服苯二氮䓬类药物和β受体阻滞剂联合治疗有效。对用于治疗红斑性肢痛症的两类药物的阳性反应支持了这种疾病在生殖器区域局部表现的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e759/3085391/b06b808b3a9e/CRIM2011-374167.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e759/3085391/b06b808b3a9e/CRIM2011-374167.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e759/3085391/b06b808b3a9e/CRIM2011-374167.001.jpg

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本文引用的文献

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Patient education and self-advocacy: queries and responses on pain management; erythromelalgia.患者教育与自我维权：关于疼痛管理的问答；红斑性肢痛症
J Pain Palliat Care Pharmacother. 2009;23(3):295-7. doi: 10.1080/15360280903099067.
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Case reports: red scrotal syndrome: a localized phenotypical expression of erythromelalgia.
J Drugs Dermatol. 2007 Sep;6(9):935-6.
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Erythromelalgia.红斑性肢痛症
Curr Treat Options Cardiovasc Med. 2006 Apr;8(2):153-65. doi: 10.1007/s11936-006-0008-8.
儿科患者的红斑性肢痛症：计算机断层扫描引导下腰交感神经阻滞的作用
J Pain Res. 2016 Oct 18;9:837-845. doi: 10.2147/JPR.S110688. eCollection 2016.
4
Erythema associated with pain and warmth on face and ears: a variant of erythermalgia or red ear syndrome?面部和耳部伴有疼痛和温热感的红斑：红斑痛或红耳综合征的一种变异型？
J Headache Pain. 2014 Mar 26;15(1):18. doi: 10.1186/1129-2377-15-18.
4
Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia.原发性红斑性肢痛症患者中编码钠通道α亚基的SCN9A基因发生突变。
J Med Genet. 2004 Mar;41(3):171-4. doi: 10.1136/jmg.2003.012153.
5
The primary erythermalgia-susceptibility gene is located on chromosome 2q31-32.原发性红斑性肢痛症易感基因位于2号染色体的31-32区。
Am J Hum Genet. 2001 May;68(5):1277-82. doi: 10.1086/320107. Epub 2001 Mar 20.
6
Erythromelalgia: new theories and new therapies.红斑性肢痛症：新理论与新疗法
J Am Acad Dermatol. 2000 Nov;43(5 Pt 1):841-7. doi: 10.1067/mjd.2000.109301.
7
Natural history of erythromelalgia: presentation and outcome in 168 patients.红斑性肢痛症的自然病史：168例患者的临床表现与转归
Arch Dermatol. 2000 Mar;136(3):330-6. doi: 10.1001/archderm.136.3.330.
8
Acute secondary erythermalgia and hypertension in children. Erythermalgia Multidisciplinary Study Group.儿童急性继发性红斑性肢痛症与高血压。红斑性肢痛症多学科研究组
Eur J Pediatr. 1995 Nov;154(11):882-5. doi: 10.1007/BF01957497.
9
Thrombocythemic erythromelalgia, primary erythermalgia, and secondary erythermalgia: three distinct clinicopathologic entities.血小板增多性红斑性肢痛症、原发性红斑性肢痛症和继发性红斑性肢痛症：三种不同的临床病理实体。
Angiology. 1994 Jun;45(6):451-3. doi: 10.1177/000331979404500606.
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Erythromelalgia in a patient with systemic lupus erythematosus treated with clonazepam.一名系统性红斑狼疮患者用氯硝西泮治疗后的红斑性肢痛症
J Rheumatol. 1990 Jan;17(1):120.