描绘美国-墨西哥边境沿线的结核病基因型集群。
Characterizing tuberculosis genotype clusters along the United States-Mexico border.
作者信息
Baker B J, Moonan P K
机构信息
Epidemic Intelligence Service, and Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
出版信息
Int J Tuberc Lung Dis. 2014 Mar;18(3):289-91. doi: 10.5588/ijtld.13.0684.
We examined the growth of tuberculosis (TB) genotype clusters during 2005-2010 in the United States, categorized by country of origin and ethnicity of the index case and geographic proximity to the US-Mexico border at the time of TB diagnosis. Nationwide, 38.9% of cases subsequent to Mexico-born index cases were US-born. Among clusters following US-born Hispanic and US-born non-Hispanic index cases, respectively 29.2% and 5.3% of subsequent cluster members were Mexico-born. In border areas, the majority of subsequent cases were Mexico-born following US-born Hispanic (56.4%) and US-born non-Hispanic (55.6%) index cases. These findings suggest that TB transmission commonly occurs between US-born and Mexico-born persons. Along the US-Mexico border, prioritizing TB genotype clusters following US-born index cases for investigation may prevent subsequent cases among both US-born and Mexico-born persons.
我们研究了2005年至2010年期间美国结核病（TB）基因型簇的增长情况，按索引病例的原籍国、种族以及结核病诊断时与美墨边境的地理距离进行分类。在全国范围内，墨西哥出生的索引病例之后的病例中有38.9%是在美国出生的。在美国出生的西班牙裔和非西班牙裔索引病例之后的簇中，后续簇成员分别有29.2%和5.3%是在墨西哥出生的。在边境地区，在美国出生的西班牙裔（56.4%）和非西班牙裔（55.6%）索引病例之后，大多数后续病例是在墨西哥出生的。这些发现表明，结核病传播通常发生在美国出生和墨西哥出生的人之间。在美国与墨西哥边境沿线，优先对美国出生的索引病例之后的结核病基因型簇进行调查，可能会预防美国出生和墨西哥出生的人当中的后续病例。
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