MMWR Morb Mortal Wkly Rep. 2014 Mar 28;63(12):270-1.
Heartland virus is a newly identified phlebovirus that was first isolated from two northwestern Missouri farmers hospitalized with fever, leukopenia, and thrombocytopenia in 2009. Based on the patients' clinical findings and their reported exposures, the virus was suspected to be transmitted by ticks. After this discovery, CDC worked with state and local partners to define the ecology and modes of transmission of Heartland virus, develop diagnostic assays, and identify additional cases to describe the epidemiology and clinical disease. From this work, it was learned that Heartland virus is found in the Lone Star tick (Amblyomma americanum). Six additional cases of Heartland virus disease were identified during 2012-2013; four of those patients were hospitalized, including one with comorbidities who died.
心域病毒是一种新鉴定的黄病毒，于 2009 年首次从密苏里州西北部两名因发热、白细胞减少和血小板减少而住院的农民身上分离出来。根据患者的临床发现和报告的暴露情况，怀疑该病毒是通过蜱传播的。这一发现之后，美国疾病控制与预防中心与州和地方合作伙伴合作，以确定心域病毒的生态和传播方式，开发诊断检测方法，并发现更多病例以描述其流行病学和临床疾病。从这项工作中了解到，心域病毒存在于孤星蜱（美洲钝缘蜱）中。在 2012-2013 年期间又发现了 6 例心域病毒病病例；其中 4 例患者住院，包括 1 例合并症患者死亡。
