Wadsworth Center, New York State Department of Health, Griffin Laboratory, 5668 State Farm Road, Slingerlands, NY 12159, USA.
Department of Biomedical Sciences, School of Public Health, State University of New York University at Albany, Rensselaer, NY 12144, USA.
J Med Entomol. 2023 Nov 14;60(6):1183-1196. doi: 10.1093/jme/tjad060.
Heartland (HRTV) and Bourbon (BRBV) viruses are newly identified tick-borne viruses, isolated from serious clinical cases in 2009 and 2014, respectively. Both viruses originated in the lower Midwest United States near the border of Missouri and Kansas, cause similar disease manifestations, and are presumably vectored by the same tick species, Amblyomma americanum Linnaeus (Ixodida: Ixodidae). In this article, we provide a current review of HRTV and BRBV, including the virology, epidemiology, and ecology of the viruses with an emphasis on the tick vector. We touch on current challenges of vector control and surveillance, and we discuss future directions in the study of these emergent pathogens.
心脏地带病毒（Heartland virus，HRTV）和波旁病毒（Bourbon virus，BRBV）是两种新鉴定的蜱传病毒，分别于 2009 年和 2014 年从严重临床病例中分离得到。这两种病毒均起源于美国中西部下地区，靠近密苏里州和堪萨斯州的边界，引起相似的疾病表现，可能由同一蜱种（美洲钝缘蜱，Amblyomma americanum Linnaeus）传播。在本文中，我们对 HRTV 和 BRBV 进行了综述，包括病毒的病毒学、流行病学和生态学，重点介绍了蜱媒介。我们还讨论了当前在媒介控制和监测方面面临的挑战，并探讨了对这些新兴病原体进行研究的未来方向。
