一名接受高效抗逆转录病毒治疗的30岁男性患者出现了一种艾滋病定义性肿瘤：这是一个被遗忘的诊断吗？
An AIDS-defining neoplasm in a 30-year-old man on highly active antiretroviral therapy: a forgotten diagnosis?
作者信息
Russell Mark D, Singh-Ranger Deepak, Crosbie James
机构信息
University College Hospital, London, UK.
出版信息
BMJ Case Rep. 2014 Mar 26;2014:bcr2013202669. doi: 10.1136/bcr-2013-202669.
Abstract
Highly active antiretroviral therapy (HAART) has dramatically improved the morbidity and mortality of patients with HIV. Although the incidence of AIDS-defining neoplasms is decreasing with this therapy, they must still be considered in patients who present with suspicious symptoms. Early diagnosis and treatment may help to improve quality of life and clinical outcome. We report the case of a 30-year-old man on HAART who presented with an expanding lump in the left groin, thought to be a haematoma for 5 months. A high level of suspicion led to a prompt diagnosis of Burkitt's lymphoma followed by timely treatment with chemotherapy. This culminated in complete remission, with an improved quality of life.
摘要
高效抗逆转录病毒疗法（HAART）显著改善了HIV患者的发病率和死亡率。尽管随着这种疗法，艾滋病相关肿瘤的发病率在下降，但对于出现可疑症状的患者，仍必须考虑到这些肿瘤。早期诊断和治疗可能有助于改善生活质量和临床结局。我们报告了一例30岁接受HAART治疗的男性患者，其左腹股沟出现一个不断增大的肿块，被认为是血肿已有5个月。高度的怀疑导致迅速诊断出伯基特淋巴瘤，随后及时进行化疗。最终实现了完全缓解，生活质量得到改善。
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