Eren Erdem, Harman Ece, Arslanoğlu Seçil, Önal Kazım
İzmir Katip Çelebi University Atatürk Research and Education Hospital, Otolaryngology Head and Neck Surgery Clinic, Konak/İzmir, Turkey
İzmir Katip Çelebi University Atatürk Research and Education Hospital, Endocrinology Clinic, Konak/İzmir, Turkey.
Otolaryngol Head Neck Surg. 2014 Jun;150(6):1033-9. doi: 10.1177/0194599814527574. Epub 2014 Mar 26.
To demonstrate if cochleopathy in patients with type 2 diabetes with normal audiometric hearing threshold can be detected with otoacoustic emissions or medial olivocochlear (MOC) reflex measurements.
Cross-sectional study.
Tertiary university teaching hospital.
The study involved 40 type 2 diabetic patients and 24 healthy volunteers. All participants who showed normal otoscopic findings, hearing thresholds, and acoustic admittance were included. Cochlear activity of participants was evaluated by means of distortion product otoacoustic emissions (DPOAEs) and transient otoacoustic emissions (TOAEs). The MOC reflex was evoked with contralateral acoustic stimulation and recorded with DPOAEs and TOAEs.
A comparison of DPOAE and TOAE levels with a t test between patient and control groups revealed no significant difference (P > .05). A comparison of the MOC reflex response between the 2 groups also revealed no statistically significant difference (P > .05).
Although decreased OAE amplitude levels were found in diabetic patients, there was no statistically significant difference in OAEs and MOC reflex. Additional studies are needed to evaluate the role of OAEs and MOC reflex in normal-hearing patients with diabetes.
探讨对于纯音听力阈值正常的2型糖尿病患者，是否可通过耳声发射或内侧橄榄耳蜗（MOC）反射测量来检测耳蜗病变。
横断面研究。
大学三级教学医院。
本研究纳入40例2型糖尿病患者和24名健康志愿者。所有受试者耳镜检查、听力阈值及声导纳均正常。采用畸变产物耳声发射（DPOAE）和瞬态耳声发射（TOAE）评估受试者的耳蜗活动。通过对侧声刺激诱发MOC反射，并用DPOAE和TOAE进行记录。
患者组与对照组之间采用t检验比较DPOAE和TOAE水平，差异无统计学意义（P>.05）。两组间MOC反射反应比较也无统计学差异（P>.05）。
尽管糖尿病患者耳声发射幅度水平降低，但耳声发射和MOC反射无统计学显著差异。需要进一步研究来评估耳声发射和MOC反射在听力正常的糖尿病患者中的作用。
