Choubisa S L
Parasitology and Toxicology Research Laboratory, Post Graduate Department of Zoology, Government Meera Girls College, Udaipur, Rajasthan, 313001, India,
Environ Monit Assess. 2014 Jul;186(7):4493-8. doi: 10.1007/s10661-014-3713-x. Epub 2014 Mar 27.
Relative susceptibility to fluoride (F) toxicosis in the form of osteo-dental fluorosis was observed in an observational survey of 2,747 mature and 887 immature domestic animals of diverse species living in areas with naturally fluoridated (>1.5 ppm F) drinking water. These animals included buffaloes (Bubalus bubalis), cattle (Bos taurus), camels (Camelus dromedarius), donkeys (Equus asinus), horses (Equus caballus), goats (Capra hircus), and sheep (Ovis aries). Of these mature and immature animals, 899 (32.7 %) and 322 (36.3 %) showed evidence of dental fluorosis with varying grades, respectively. Their incisor teeth were stained with light to deep brownish color. On clinical examination, 31.2 % mature and 10.7 % immature animals revealed periosteal exostoses, intermittent lameness, and stiffness of tendons in the legs as signs of skeletal fluorosis. The maximum susceptibility to fluoride toxicosis was found in bovines (buffaloes and cattle) followed by equines (donkeys and horses), flocks (goats and sheep), and camelids (camels). The bovine calves were found to be more sensitive and highly susceptible to F toxicosis and revealed the maximum prevalence (92.2 %) of dental fluorosis. This indicates that bovine calves are less tolerant and give early sign of F poisoning (dental fluorosis) and therefore, they can be considered as bio-indicators for fluoridated water as well as for endemicity of osteo-dental fluorosis. Causes for variation in susceptibility to F toxicosis (fluorosis) in various species of domestic animal are also discussed.
在一项观察性调查中，对生活在天然氟含量（>1.5 ppm氟）饮用水地区的2747头成年和887头未成年的不同物种家畜，观察了它们对氟中毒（以骨牙氟中毒形式）的相对易感性。这些动物包括水牛（Bubalus bubalis）、牛（Bos taurus）、骆驼（Camelus dromedarius）、驴（Equus asinus）、马（Equus caballus）、山羊（Capra hircus）和绵羊（Ovis aries）。在这些成年和未成年动物中，分别有899头（32.7%）和322头（36.3%）显示出不同程度的牙氟中毒迹象。它们的门牙被染成浅至深褐色。临床检查发现，31.2%的成年动物和10.7%的未成年动物表现出骨膜外生骨疣、间歇性跛行和腿部肌腱僵硬等骨骼氟中毒症状。发现对氟中毒易感性最高的是牛（水牛和牛），其次是马科动物（驴和马）、羊群（山羊和绵羊）和骆驼科动物（骆驼）。发现牛犊对氟中毒更敏感且高度易感，牙氟中毒患病率最高（92.2%）。这表明牛犊对氟的耐受性较低，会较早出现氟中毒迹象（牙氟中毒），因此，它们可被视为氟化物水以及骨牙氟中毒地方性流行的生物指标。还讨论了不同家畜物种对氟中毒（氟病）易感性差异的原因。
