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百草枯中毒:一例病例报告及文献综述

Paraquat poisoning: A case report and review of literature.

作者信息

Raghu Kondle, Mahesh Vidavalur, Sasidhar Parri, Reddy Polam R, Venkataramaniah Vajja, Agrawal Amit

机构信息

Department of Emergency Medicine, Narayana Medical College Hospital, Chinthareddypalem, Nellore, Andhra Pradesh, India.

Department of Medicine, Narayana Medical College Hospital, Chinthareddypalem, Nellore, Andhra Pradesh, India.

出版信息

J Family Community Med. 2013 Sep;20(3):198-200. doi: 10.4103/2230-8229.122023.

Abstract

Paraquat (1, r-dimethyl-4,4'-bipyridium dichloride), a brown syrupy liquid is an effective herbicide that has low chronic toxicity because of its rapid deactivation on contact with soil. A high dose of paraquat or severe poisoning has a poor prognosis. At present there is no specific antidote to paraquat poisoning, hence the need to focus on prevention and in case of exposure or ingestion, aggressive decontamination to prevent further absorption. Although uncommon, paraquat ingestion can lead to severe and often fatal toxicity. However, despite its widespread availability, reports of this herbicide poisoning in India are uncommon.

摘要

百草枯(1,1'-二甲基-4,4'-联吡啶二氯化物)是一种棕色糖浆状液体,是一种有效的除草剂,由于其与土壤接触后会迅速失活,因此慢性毒性较低。高剂量百草枯或严重中毒预后不良。目前尚无针对百草枯中毒的特效解毒剂,因此需要着重于预防,一旦接触或摄入,应积极进行去污处理以防止进一步吸收。尽管百草枯摄入并不常见,但可能导致严重且往往致命的毒性。然而,尽管这种除草剂广泛可得,但印度关于其中毒的报告却并不常见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e2e/3957175/876793248096/JFCM-20-198-g001.jpg

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