Safaei Asl Afshin, Dadashzadeh Peyman
Division of Nephrology, Department of Pediatrics, Guilan University of Medical Sciences, Rasht, Iran.
Resident of Pediatrics , Guilan University of Medical Sciences, Rasht, Iran.
J Renal Inj Prev. 2016 Aug 3;5(4):203-6. doi: 10.15171/jrip.2016.43. eCollection 2016.
Paraquat and diquat are classified as bipyridyl compounds not only leads to acute organ damage, but also to a variety of complications. Patients with severe paraquat-induced poisoning may succumb to multiple organ failure involving the circulatory and respiratory systems. Deliberate self-poisoning with paraquat continues to be a major public health concern in many developing countries. At present there is no specific antidote to paraquat poisoning, hence the need to more focus on prevention and in cases of poisoning aggressive decontamination to prevent further absorption. This article presented a 12-year-old male with acute kidney injury following the ingestion of paraquat in suicidal attempt and serves to explore the complications associated with paraquat poisoning and current recommended treatment.
百草枯和敌草快属于联吡啶类化合物，不仅会导致急性器官损伤，还会引发多种并发症。百草枯中毒严重的患者可能会死于涉及循环和呼吸系统的多器官功能衰竭。在许多发展中国家，故意自服百草枯中毒仍然是一个重大的公共卫生问题。目前尚无针对百草枯中毒的特效解毒剂，因此需要更加注重预防，对于中毒病例要积极进行去污处理以防止进一步吸收。本文介绍了一名12岁男性因自杀性吞服百草枯后出现急性肾损伤的病例，并探讨了与百草枯中毒相关的并发症及当前推荐的治疗方法。
