Janeela M Asisha, Oommen Ajoy, Misra Ajay Kumar, Ramya I
Department of General Medicine, Christian Medical College, Vellore, Tamil Nadu, India.
J Family Med Prim Care. 2017 Jul-Sep;6(3):672-673. doi: 10.4103/2249-4863.222042.
N, N'-dimethyl-4, 4'-bipyridinium dichloride (paraquat) is a widely used synthetic, nonselective contact herbicide. Ingestion of toxic doses of paraquat can be fatal with life-threatening effects on the lungs, gastrointestinal (GI) tract, kidney, liver, heart, and other organs. Till date, there are no specific antidotes and none of the current treatments have proven efficacious. The prognosis is uniformly poor worldwide, including those who treat aggressively with multimodal therapies. Long-term survivors are few, and have GI and pulmonary complications. Hence, prevention needs to be the utmost priority, and on exposure, aggressive decontamination should be initiated. Although it is a very common herbicide, there are very few cases reported from India and awareness among people needs to be widened.
N，N'-二甲基-4,4'-联吡啶二氯化物（百草枯）是一种广泛使用的合成非选择性接触性除草剂。摄入有毒剂量的百草枯可能致命，会对肺部、胃肠道、肾脏、肝脏、心脏和其他器官产生危及生命的影响。迄今为止，尚无特效解毒剂，目前的治疗方法均未被证明有效。在全球范围内，预后普遍较差，包括那些接受多模式积极治疗的患者。长期存活者很少，且有胃肠道和肺部并发症。因此，预防应是重中之重，一旦接触，应立即进行积极的去污处理。尽管它是一种非常常见的除草剂，但印度报告的病例很少，需要提高人们的认识。
