Park Jeong Kyu, Kim Sung Kyu, Cho Ihn Ho, Kong Eun Jung
Department of Radiologic Technology, Daegu Health College, Youngsong-ro 15, Buk-gu, Daegu 702-722, Republic of Korea.
Department of Therapeutic Radiology & Oncology, College of Medicine, Yeungnam University, Nam-gu, Daegu 705-717, Republic of Korea.
ScientificWorldJournal. 2014 Feb 4;2014:194925. doi: 10.1155/2014/194925. eCollection 2014.
The purpose of this research is to establish an overall data set associated with the VOI (Volume of Interest), which is available for simultaneous assessment of PET/MRI and PET/CT regardless of the use of contrast media. The participants as objects of this investigation are 26 healthy examinees in Korea, SUV (standardized-uptake-value)s-maximum evaluation for whole-body F-18 FDG (fluorodeoxyglucose) PET/MRI image using VOI of normal region has exhibited very significant difference to that for whole-body F-18 FDG PET/CT image (significant probability value (P) < 0.0001). However, there appeared high correlation between them in view of statistics (R-square (R) > 0.8). It is shown that one needs to decide SUVs-maximum for PET/MRI with the reduction of 25.026.4% from their evaluated value and needs to decide with the reduction of 28.829.4% in the same situation but with the use of contrast media. The use of SUVLBM-maximum (SUVLean Body Mass-maximum) is very advantageous in reading overall image of PET/CT and PET/MRI to medical doctors and researchers, if we consider its convenience and efficiency. We expect that this research enhances the level of the early stage accurate diagnosis with whole-body images of PET/MRI and PET/CT.
本研究的目的是建立一个与感兴趣容积(VOI)相关的整体数据集,该数据集可用于在不考虑是否使用造影剂的情况下同时评估PET/MRI和PET/CT。本调查的对象是26名韩国健康受试者,使用正常区域的VOI对全身F-18 FDG(氟脱氧葡萄糖)PET/MRI图像进行SUV(标准化摄取值)-最大值评估,与全身F-18 FDG PET/CT图像相比显示出非常显著的差异(显著性概率值(P)<0.0001)。然而,从统计学角度来看,它们之间存在高度相关性(决定系数(R)>0.8)。结果表明,对于PET/MRI,需要将SUV最大值从其评估值降低25.0%至26.4%来确定,而在相同情况下但使用造影剂时,则需要降低28.8%至29.4%来确定。如果考虑到其便利性和效率,使用SUVLBM-最大值(瘦体重标准化摄取值-最大值)对医生和研究人员阅读PET/CT和PET/MRI的整体图像非常有利。我们期望这项研究能够提高PET/MRI和PET/CT全身图像的早期准确诊断水平。