因可卡因掺假导致的苯妥英中毒。
Phenytoin toxicity from cocaine adulteration.
作者信息
Roldan Carlos J
机构信息
Department of Emergency Medicine, University of Texas Health Science Center at Houston, Houston, Texas.
出版信息
West J Emerg Med. 2014 Mar;15(2):127-30. doi: 10.5811/westjem.2013.12.20010.
The use of phenytoin (PHT) as a cocaine adulterant was reported decades ago; that practice is still current. Ironically PHT has also been used for the treatment of cocaine dependence. A drug smuggler developed PHT toxicity after swallowing several rocks of crack. We investigated the current trends of PHT as a cocaine adulterant and its toxicological implications. We also reviewed the clinical use of PTH in relation to cocaine. The use of PHT as cocaine cut is a current practice. This may affect the clinical manifestations and the management of the cocaine-related visits to the emergency department.
几十年前就有关于使用苯妥英（PHT）作为可卡因掺杂物的报道；这种做法至今仍存在。具有讽刺意味的是，PHT也被用于治疗可卡因依赖。一名毒品走私者在吞下几块快克可卡因后出现了PHT中毒。我们调查了PHT作为可卡因掺杂物的当前趋势及其毒理学影响。我们还回顾了PTH与可卡因相关的临床应用。使用PHT作为可卡因的稀释剂是目前的一种做法。这可能会影响可卡因相关急诊就诊的临床表现和处理。
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