Director of Anaesthesia Research, Department of Anaesthesia, The Royal Women's Hospital Parkville, Parkville, Victoria, Australia; Department of Pharmacology and Department of Obstetrics and Gynaecology, The University of Melbourne, Melbourne, Victoria, Australia.
Anaesthesia. 2014 May;69(5):436-44. doi: 10.1111/anae.12623. Epub 2014 Mar 27.
The aim of this study was to investigate cardiac function and haemodynamic indices using transthoracic echocardiography in women with severe pre-eclampsia who had already received treatment interventions. Fifteen women with treated severe pre-eclampsia were studied using transthoracic echocardiography. Mean (SD) cardiac output in women with treated disease was 5690 (1708) ml.min(-1). Systolic function was preserved in women with treated disease evidenced by mean (SD) fractional shortening 41 (9)%, fractional area change 62 (12)% and septal s' velocities 9.0 (2.1) cm.s(-1). Left ventricle end-diastolic diameters were within healthy reference ranges at 4.7 (0.3) cm and the left ventricle was not dilated. Diastolic function was reduced, with a mean (SD) mitral valve E/septal e' ratio of 12.6 (4.1). Left ventricular mass was increased at 182.0 (44.4) g. There was large variability in haemodynamics in women with treated severe pre-eclampsia. Transthoracic echocardiography is acceptable and applicable and enables quantification of cardiac function in women with severe pre-eclampsia.
本研究旨在通过经胸超声心动图调查已接受治疗干预的重度子痫前期女性的心脏功能和血液动力学指标。对 15 名经治疗的重度子痫前期女性进行经胸超声心动图检查。治疗疾病女性的平均（标准差）心输出量为 5690（1708）ml.min(-1)。治疗疾病女性的收缩功能正常，平均（标准差）分数缩短 41（9）%，分数面积变化 62（12）%和间隔 s'速度 9.0（2.1）cm.s(-1)。左心室舒张末期直径为 4.7（0.3）cm，处于健康参考范围内，且左心室未扩张。舒张功能降低，二尖瓣 E/间隔 e' 比值平均（标准差）为 12.6（4.1）。左心室质量增加到 182.0（44.4）g。治疗重度子痫前期女性的血液动力学存在很大差异。经胸超声心动图是可接受和适用的，能够定量评估重度子痫前期女性的心脏功能。
