Lawrence Paulraj K, Bey Russell F, Wiener Brittanny, Kittichotirat Weerayuth, Bumgarner Roger E
Newport Laboratories Ltd., Worthington, Minnesota, USA.
Genome Announc. 2014 Mar 27;2(2):e00114-14. doi: 10.1128/genomeA.00114-14.
Mannheimia haemolytica is a Gram-negative bacterium and the principal etiological agent associated mostly with bovine respiratory disease complex. However, we report here the sequence of a strain with the novel A1/A6-cross-reactive serotype, strain PKL10, isolated from white-tailed deer. PKL10 was isolated from the spleen of farmed white-tailed deer showing clinical signs of pneumonia. The genome structure of PKL10 is dramatically different from that of previously sequenced isolates, which was demonstrated by genome alignments. In addition, the coding sequences in PKL10 share approximately 86% sequence identity with the coding sequences in other fully sequenced M. haemolytica strains. This suggests that PKL10 is a novel Mannheimia species.
溶血曼氏杆菌是一种革兰氏阴性菌,也是主要与牛呼吸道疾病综合征相关的病原体。然而,我们在此报告从白尾鹿分离出的具有新型A1/A6交叉反应血清型的菌株PKL10的序列。PKL10是从表现出肺炎临床症状的养殖白尾鹿的脾脏中分离出来的。通过基因组比对证明,PKL10的基因组结构与先前测序的分离株有显著差异。此外,PKL10中的编码序列与其他全序列溶血曼氏杆菌菌株中的编码序列具有约86%的序列同一性。这表明PKL10是一种新型的曼氏杆菌物种。