心境正常的双相情感障碍患者的感觉运动表现：MPraxis（宾夕法尼亚大学认知神经精神病学项目）分析
Sensorimotor performance in euthymic bipolar disorder: the MPraxis (PennCNP) analysis.
作者信息
Neves Maila de C, Albuquerque Maicon R, Neves Fernando S, Lage Guilherme M, Malloy-Diniz Leandro, Nicolato Rodrigo, Corrêa Humberto
机构信息
Mental Health Department, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.
Physical Education Department, Universidade Federal de Viçosa (UFV), Viçosa, MG, Brazil.
出版信息
Braz J Psychiatry. 2014 Sep;36(3):248-50. doi: 10.1590/1516-4446-2013-1243. Epub 2014 Mar 17.
BACKGROUND
Sensorimotor deficits are an important phenomenological facet observed in patients with bipolar disorder (BD). However, there is little research on this topic. We hypothesize that the MPraxis test can be used to screen for motor impairments in BD aiming movements.
METHOD
The MPraxis, which is a quick and easy-to-apply computerized test, measures sensorimotor control. During the test, the participant must move the computer mouse cursor over an ever-shrinking green box and click on it once. We predict that the MPraxis test is capable of detecting differences in sensorimotor performance between patients with BD and controls. We assessed 21 euthymic type I BD patients, without DSM-IV-TR Axis I comorbidity, and 21 healthy controls.
RESULTS AND CONCLUSIONS
Compared to the controls, the patients with BD presented a lower response time in their movements in all conditions. Our results showed sensorimotor deficits in BD and suggested that the MPraxis test can be used to screen for motor impairments in patients with euthymic BD.
背景
感觉运动功能障碍是双相情感障碍（BD）患者中观察到的一个重要现象学方面。然而，关于这个主题的研究很少。我们假设MPraxis测试可用于筛查BD患者目标导向运动中的运动障碍。
方法
MPraxis是一种快速且易于应用的计算机化测试，用于测量感觉运动控制。在测试过程中，参与者必须将电脑鼠标光标移到一个不断缩小的绿色框上并点击一次。我们预测MPraxis测试能够检测出BD患者与对照组之间感觉运动表现的差异。我们评估了21名无DSM-IV-TR轴I共病的I型心境正常的BD患者和21名健康对照者。
结果与结论
与对照组相比，BD患者在所有条件下的运动反应时间均较短。我们的结果显示BD患者存在感觉运动功能障碍，并表明MPraxis测试可用于筛查心境正常的BD患者的运动障碍。
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