Shapiro Lauren M, McWalter Emily J, Son Min-Sun, Levenston Marc, Hargreaves Brian A, Gold Garry E
Department of Radiology, Stanford University, Stanford, California, USA.
J Magn Reson Imaging. 2014 Jun;39(6):1346-56. doi: 10.1002/jmri.24562. Epub 2014 Feb 19.
Osteoarthritis has grown to become a widely prevalent disease that has major implications in both individual and public health. Although originally considered to be a degenerative disease driven by "wear and tear" of the articular cartilage, recent evidence has led to a consensus that osteoarthritis pathophysiology should be perceived in the context of the entire joint and multiple tissues. MRI is becoming an increasingly more important modality for imaging osteoarthritis, due to its excellent soft tissue contrast and ability to acquire morphological and biochemical data. This review will describe the pathophysiology of osteoarthritis as it is associated with various tissue types, highlight several promising MR imaging techniques for osteoarthritis and illustrate the expected appearance of osteoarthritis with each technique.
骨关节炎已发展成为一种广泛流行的疾病，对个人和公共健康都有重大影响。尽管最初被认为是一种由关节软骨“磨损”驱动的退行性疾病，但最近的证据已达成共识，即应从整个关节和多种组织的角度来认识骨关节炎的病理生理学。由于其出色的软组织对比度以及获取形态学和生化数据的能力，磁共振成像（MRI）正日益成为骨关节炎成像的重要手段。本综述将描述与各种组织类型相关的骨关节炎的病理生理学，重点介绍几种有前景的骨关节炎磁共振成像技术，并说明每种技术下骨关节炎的预期表现。
