关节软骨生理学的磁共振成像
MR imaging of articular cartilage physiology.
作者信息
Choi Jung-Ah, Gold Garry E
机构信息
Department of Radiology, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA.
出版信息
Magn Reson Imaging Clin N Am. 2011 May;19(2):249-82. doi: 10.1016/j.mric.2011.02.010.
Abstract
The newer magnetic resonance (MR) imaging methods can give insights into the initiation, progression, and eventual treatment of osteoarthritis. Sodium imaging is specific for changes in proteoglycan (PG) content without the need for an exogenous contrast agent. T1ρ imaging is sensitive to early PG depletion. Delayed gadolinium-enhanced MR imaging has high resolution and sensitivity. T2 mapping is straightforward and is sensitive to changes in collagen and water content. Ultrashort echo time MR imaging examines the osteochondral junction. Magnetization transfer provides improved contrast between cartilage and fluid. Diffusion-weighted imaging may be a valuable tool in postoperative imaging.
摘要
更新的磁共振（MR）成像方法能够深入了解骨关节炎的起始、进展及最终治疗情况。钠成像对蛋白聚糖（PG）含量变化具有特异性，无需外源性对比剂。T1ρ成像对早期PG耗竭敏感。延迟钆增强磁共振成像具有高分辨率和高灵敏度。T2成像简单直接，对胶原蛋白和水含量的变化敏感。超短回波时间磁共振成像可检查骨软骨交界处。磁化传递可改善软骨与液体之间的对比度。扩散加权成像可能是术后成像中的一种有价值的工具。
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