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后路及经椎间孔腰椎椎间融合术(PLIF/TLIF)治疗腰椎局限性节段退变

[Posterior and transforaminal lumbar interbody fusion (PLIF/TLIF) for the treatment of localised segment degeneration of lumbar spine].

作者信息

Kunze B, Drasseck T, Kluba T

机构信息

Orthopädische Universitätsklinik Tübingen.

出版信息

Z Orthop Unfall. 2011 Jun;149(3):312-6. doi: 10.1055/s-0030-1250689. Epub 2011 Feb 21.

Abstract

BACKGROUND

Chronic intractable low back pain is one of the most common orthopaedic diagnoses, with an enormous socioeconomic impact. The surgical treatment by posterior transpedicular instrumentation and interbody fusion of the affected segments is an established procedure after exhaustion of conservative therapies. Due to different study data on the clinical and functional results after posterior (PLIF) and transforaminal (TLIF) interbody fusion, our own patient population was analysed retrospectively.

PATIENTS AND METHODS

Included were 143 patients who had been treated surgically at our institution between 1999 and 2006 by one of the two methods (PLIF, n = 68; TLIF, n = 75). In addition to general demographic data, results of three questionnaires (Oswestry disability index, numeric rating scale, Roland Morris score) were retrospectively analysed before surgery and in the general follow-up - identifying clinical and functional results of patient satisfaction.

RESULTS

All patients had been suffering in spite of the exhaustion of conservative therapies for at least six months of chronic low back pain prior to surgery. The mean age at surgery was 52 years. The complication rate was 23 %, the revision rate 15 %. Overall, there was a high patient satisfaction in follow-up. In ODI, a significant decrease in pain-related disability was observed from 49.8 % preoperatively to 24.7 % after surgery (p < 0.0001). This functional improvement was present in all aetiological subgroups irrespective of the fusion length. A statistically significantly better functional outcome was achieved in the ODI in the PLIF group (improvement 27.2 % vs. 23.1 %, p < 0.0001). The preoperative baseline regarding pain was assessed in the NRS on average at 6.5 points. Postoperatively, it decreased to 3.34 points (p < 0.0001). The functional limitation due to existing back pain was assessed preoperatively with an average of 13.08 points. Postoperatively a significant reduction to 6.19 points was observed (p < 0.0001). Group- or operation-specific differences were not statistically significant.

CONCLUSION

The data of this study indicate that both TLIF and PLIF techniques are possible surgical treatment methods for patients with resistant chronic low back pain. With both techniques a clear benefit regarding quality of life and function for the operated patients is achievable, if the correct surgical indication is given.

摘要

背景

慢性顽固性腰痛是最常见的骨科诊断之一,具有巨大的社会经济影响。在保守治疗无效后,通过后路经椎弓根器械固定和病变节段椎间融合进行手术治疗是一种既定的方法。由于关于后路(PLIF)和经椎间孔(TLIF)椎间融合术后临床和功能结果的研究数据不同,我们对自己的患者群体进行了回顾性分析。

患者与方法

纳入了1999年至2006年期间在我们机构接受这两种方法之一(PLIF,n = 68;TLIF,n = 75)手术治疗的143例患者。除了一般人口统计学数据外,还对三份问卷(Oswestry功能障碍指数、数字评分量表、罗兰·莫里斯评分)的结果在手术前和总体随访中进行了回顾性分析,以确定患者满意度的临床和功能结果。

结果

所有患者尽管保守治疗无效,但在手术前都患有慢性腰痛至少六个月。手术时的平均年龄为52岁。并发症发生率为23%,翻修率为15%。总体而言,随访中的患者满意度较高。在Oswestry功能障碍指数(ODI)方面,观察到与疼痛相关的功能障碍从术前的49.8%显著下降至术后的24.7%(p < 0.0001)。无论融合长度如何,所有病因亚组均出现这种功能改善。PLIF组在ODI方面实现了统计学上显著更好的功能结果(改善27.2%对23.1%,p < 0.0001)。术前疼痛的基线在数字评分量表(NRS)上平均评估为6.5分。术后,降至3.34分(p < 0.0001)。术前因现有腰痛导致的功能受限平均评估为13.08分。术后观察到显著降至6.19分(p < 0.0001)。组间或手术特异性差异无统计学意义。

结论

本研究数据表明,TLIF和PLIF技术都是治疗顽固性慢性腰痛患者的可行手术方法。如果给出正确的手术指征,两种技术都可以为手术患者在生活质量和功能方面带来明显益处。

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