Undergraduation on Federal University of Rio Grande do Sul, Brazil; Graduate Program in Epidemiology, Federal University of Rio Grande do Sul, Brazil.
Undergraduation on Federal University of Rio Grande do Sul, Brazil.
Food Chem. 2014 Aug 15;157:310-22. doi: 10.1016/j.foodchem.2014.02.046. Epub 2014 Feb 22.
Acrylamide (AA) is a probable human carcinogen found in carbohydrate-rich foods that have been heated to high temperatures. AA dietary exposure has been associated to development of health problems. We perform a systematic review to elucidate the association of dietary AA exposure and human health problems. Articles were screened by reading titles and abstracts before the full text of eligible articles was read (κ=0.824). Data were harvested by two reviewers and checked by a third. Forty-one articles were analyzed and assessment of dietary exposure proved to be far from uniform and suffered from limitations that possibly impact on the validity of outcomes with relation to human health. Risk assessment of dietary acrylamide exposure is in need of high quality methods for evaluating dietary exposure and validated acrylamide content databases.
丙烯酰胺（AA）是一种在高温加热的富含碳水化合物的食物中发现的可能的人类致癌物质。AA 的饮食暴露与健康问题的发展有关。我们进行了系统评价，以阐明饮食中 AA 暴露与人类健康问题的关系。通过阅读标题和摘要筛选文章，然后阅读合格文章的全文（κ=0.824）。由两名评审员收集数据，并由第三名评审员进行检查。分析了 41 篇文章，并且饮食暴露的评估远非统一，存在可能影响与人类健康有关的结果有效性的局限性。需要高质量的方法来评估饮食暴露和验证丙烯酰胺含量数据库，以进行饮食丙烯酰胺暴露的风险评估。
