• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

艾尔夏奶牛的基因组评估、品种鉴定以及影响繁殖力的单倍型发现。

Genomic evaluation, breed identification, and discovery of a haplotype affecting fertility for Ayrshire dairy cattle.

作者信息

Cooper T A, Wiggans G R, Null D J, Hutchison J L, Cole J B

机构信息

Animal Improvement Programs Laboratory, Agricultural Research Service, US Department of Agriculture (USDA), Beltsville, MD 20705-2350.

Animal Improvement Programs Laboratory, Agricultural Research Service, US Department of Agriculture (USDA), Beltsville, MD 20705-2350.

出版信息

J Dairy Sci. 2014;97(6):3878-82. doi: 10.3168/jds.2013-7427. Epub 2014 Mar 27.

DOI:10.3168/jds.2013-7427
PMID:24679938
Abstract

Genomic evaluations of dairy cattle in the United States have been available for Brown Swiss, Holsteins, and Jerseys since 2009. As of January 2013, 1,023 Ayrshires had genotypes in the North American database. Evaluation accuracy was assessed using genomic evaluations based on 646 bulls with 2008 traditional evaluations to predict daughter performance of up to 180 bulls in 2012. Mean gain in reliability over parent average for all traits was 8.2 percentage points. The highest gains were for protein yield (16.9 percentage points), milk yield (16.6 percentage points), and stature (16.2 percentage points). Twelve single nucleotide polymorphisms were useful for Ayrshire breed determination. Fewer breed-determining SNP were available for Ayrshires than for Holsteins, Jerseys, and Brown Swiss because of the similarity of Ayrshires and Holsteins. A haplotype that affects fertility was identified on chromosome 17 and traces back in the genotyped population to the bull Selwood Betty's Commander (born in 1953). The haplotype carrier frequency for genotyped Ayrshires was 26.1%. Sire conception rate was decreased by 4.3 ± 2.5 percentage points for carriers of the haplotype as determined by 618 matings of carrier sire by carrier maternal grandsire. Genomic evaluations for Ayrshires were officially implemented in the United States in April 2013.

摘要

自2009年以来,美国已对瑞士褐牛、荷斯坦奶牛和泽西奶牛进行了基因组评估。截至2013年1月,北美数据库中有1023头爱尔夏牛的基因型。利用基于646头公牛的基因组评估(这些公牛有2008年的传统评估数据)来预测2012年多达180头公牛的女儿的生产性能,以此评估评估准确性。所有性状相对于亲本平均值的可靠性平均提高了8.2个百分点。提高幅度最大的是蛋白质产量(16.9个百分点)、产奶量(16.6个百分点)和体高(16.2个百分点)。12个单核苷酸多态性可用于爱尔夏牛品种鉴定。由于爱尔夏牛与荷斯坦奶牛相似,可用于爱尔夏牛品种鉴定的单核苷酸多态性比荷斯坦奶牛、泽西奶牛和瑞士褐牛的少。在17号染色体上鉴定出一个影响繁殖力的单倍型,在已分型群体中可追溯到公牛塞尔伍德·贝蒂的指挥官(出生于1953年)。已分型爱尔夏牛的单倍型携带频率为26.1%。通过携带该单倍型的父本与携带该单倍型的母系祖父的618次交配确定,该单倍型携带者的父本受胎率降低了4.3±2.5个百分点。2013年4月,美国正式实施了爱尔夏牛的基因组评估。

相似文献

1
Genomic evaluation, breed identification, and discovery of a haplotype affecting fertility for Ayrshire dairy cattle.艾尔夏奶牛的基因组评估、品种鉴定以及影响繁殖力的单倍型发现。
J Dairy Sci. 2014;97(6):3878-82. doi: 10.3168/jds.2013-7427. Epub 2014 Mar 27.
2
Genomic evaluation, breed identification, and population structure of Guernsey cattle in North America, Great Britain, and the Isle of Guernsey.北美、英国和根西岛的根西牛基因组评估、品种鉴定及群体结构
J Dairy Sci. 2016 Jul;99(7):5508-5515. doi: 10.3168/jds.2015-10445. Epub 2016 May 11.
3
Increasing the number of single nucleotide polymorphisms used in genomic evaluation of dairy cattle.增加用于奶牛基因组评估的单核苷酸多态性数量。
J Dairy Sci. 2016 Jun;99(6):4504-4511. doi: 10.3168/jds.2015-10456. Epub 2016 Mar 31.
4
Phenotypic and genetic effects of recessive haplotypes on yield, longevity, and fertility.隐性单倍型对产量、寿命和生育力的表型及遗传效应。
J Dairy Sci. 2016 Sep;99(9):7274-7288. doi: 10.3168/jds.2015-10777. Epub 2016 Jul 7.
5
Improving accuracy of genomic predictions within and between dairy cattle breeds with imputed high-density single nucleotide polymorphism panels.利用高分辨率单核苷酸多态性面板提高奶牛品种内和品种间基因组预测的准确性。
J Dairy Sci. 2012 Jul;95(7):4114-29. doi: 10.3168/jds.2011-5019.
6
Marker selection and genomic prediction of economically important traits using imputed high-density genotypes for 5 breeds of dairy cattle.利用导入的高密度基因型对 5 个奶牛品种的经济重要性状进行标记选择和基因组预测。
J Dairy Sci. 2021 Apr;104(4):4478-4485. doi: 10.3168/jds.2020-19260. Epub 2021 Feb 19.
7
Multibreed genomic evaluations using purebred Holsteins, Jerseys, and Brown Swiss.使用纯种荷斯坦牛、娟姗牛和瑞士褐牛进行多品种基因组评估。
J Dairy Sci. 2012 Sep;95(9):5378-5383. doi: 10.3168/jds.2011-5006.
8
Genomic Selection in Dairy Cattle: The USDA Experience.奶牛基因组选择:美国农业部的经验。
Annu Rev Anim Biosci. 2017 Feb 8;5:309-327. doi: 10.1146/annurev-animal-021815-111422. Epub 2016 Nov 16.
9
The genomic evaluation system in the United States: past, present, future.美国的基因组评估系统:过去、现在和未来。
J Dairy Sci. 2011 Jun;94(6):3202-11. doi: 10.3168/jds.2010-3866.
10
Efficiency of multi-breed genomic selection for dairy cattle breeds with different sizes of reference population.不同参考群体规模的奶牛品种多品种基因组选择效率
J Dairy Sci. 2014;97(6):3918-29. doi: 10.3168/jds.2013-7761. Epub 2014 Apr 3.

引用本文的文献

1
Unravelling transmission ratio distortion across the bovine genome: identification of candidate regions for reproduction defects.揭开牛基因组中传输比失真的谜团:生殖缺陷候选区域的鉴定。
BMC Genomics. 2023 Jul 8;24(1):383. doi: 10.1186/s12864-023-09455-6.
2
Four novel candidate causal variants for deficient homozygous haplotypes in Holstein cattle.四个新的候选因果变异与荷斯坦奶牛纯合缺陷单倍型有关。
Sci Rep. 2022 Mar 31;12(1):5435. doi: 10.1038/s41598-022-09403-6.
3
Reverse Genetic Screen for Deleterious Recessive Variants in the Local Simmental Cattle Population of Switzerland.
瑞士本地西门塔尔牛群体中有害隐性变异的反向遗传筛选
Animals (Basel). 2021 Dec 12;11(12):3535. doi: 10.3390/ani11123535.
4
Mining massive genomic data of two Swiss Braunvieh cattle populations reveals six novel candidate variants that impair reproductive success.从两个瑞士褐牛群体的大量基因组数据中挖掘出六个影响繁殖成功率的新候选变异。
Genet Sel Evol. 2021 Dec 16;53(1):95. doi: 10.1186/s12711-021-00686-3.
5
Development of amplified fragment length polymorphism (AFLP) markers for the identification of Cholistani cattle.用于鉴定乔利斯坦牛的扩增片段长度多态性(AFLP)标记的开发
Arch Anim Breed. 2018 Oct 12;61(4):387-394. doi: 10.5194/aab-61-387-2018. eCollection 2018.
6
A comprehensive biomedical variant catalogue based on whole genome sequences of 582 dogs and eight wolves.基于 582 只狗和 8 只狼的全基因组序列构建的综合生物医学变异目录。
Anim Genet. 2019 Dec;50(6):695-704. doi: 10.1111/age.12834. Epub 2019 Sep 5.
7
Management of lethal recessive alleles in beef cattle through the use of mate selection software.通过使用选配软件管理肉牛中的致死隐性等位基因。
Genet Sel Evol. 2019 Aug 6;51(1):36. doi: 10.1186/s12711-019-0477-3.
8
Including gene networks to predict calving difficulty in Holstein, Brown Swiss and Jersey cattle.将基因网络纳入荷斯坦、瑞士褐牛和泽西牛的产犊难易度预测中。
BMC Genet. 2018 Apr 2;19(1):20. doi: 10.1186/s12863-018-0606-y.
9
In frame exon skipping in UBE3B is associated with developmental disorders and increased mortality in cattle.UBE3B基因中符合读码框的外显子跳跃与牛的发育障碍及死亡率增加有关。
BMC Genomics. 2014 Oct 12;15(1):890. doi: 10.1186/1471-2164-15-890.