Dong Dong, Zhao Yulin, Stewart Michael G, Sun Liang, Cheng Huijuan, Wang Jingjing, Li Weiya
Department of Rhinology, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Department of Rhinology, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China. Email:
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2014 Jan;49(1):20-6.
To develop the Chinese version of the nasal obstruction symptom evaluation (NOSE) questionnaire.
After introduction, forward and backward translation, synthesis, expert committee review, pretest, adaptation and validation followed the international guidelines, the Chinese version of NOSE scale was tested among 223 nasal septal deviation patients and 80 health volunteers to further assess its psychometric and clinical properties. SPSS 19.0 software was used to analyze the data.
The Chinese version demonstrated satisfactory evaluation results. The acceptance rate of the questionnaire was 97.6% and 94.1% in the patient group and control group respectively, and the completion time was (1.5 ± 0.5)min and (1.0 ± 0.5)min. Internal consistency reliability (Cronbach's α) was calculated to be 0.869. Test-retest reliability coefficient was adequate at rs = 0.996. Content validity was approved by our expert committee. Criteria validity (Spearman correlation coefficient) between NOSE Chinese version and SF-36, as well as VAS was -0.837 and 0.725 separately. Construct validity of Chinese version was similar to that of the original edition. The standardized response mean and the effect size at three months postoperatively was respectively 1.34 and 1.21, indicating high responsiveness. Calculated by Mann-Whitney U test, the instrument showed excellent sensitivity to discriminate the subjects with or without nasal obstruction (P < 0.01). The NOSE scores were also correlated with nasal resistance by rhinomanometry.
The NOSE Chinese version was successfully cross-cultural adapted and validated. It therefore can be recommended as a robust tool for future measuring subjective severity of nasal obstruction in China.
编制鼻阻塞症状评估（NOSE）问卷的中文版。
按照国际指南进行引入、前后翻译、综合、专家委员会评审、预测试、调整和验证后，在223例鼻中隔偏曲患者和80名健康志愿者中对中文版NOSE量表进行测试，以进一步评估其心理测量学和临床特性。使用SPSS 19.0软件进行数据分析。
中文版显示出令人满意的评估结果。问卷在患者组和对照组中的接受率分别为97.6%和94.1%，完成时间分别为（1.5±0.5）分钟和（1.0±0.5）分钟。内部一致性信度（Cronbach'sα）计算为0.869。重测信度系数在rs=0.996时足够。内容效度经专家委员会认可。中文版NOSE与SF-36以及视觉模拟量表（VAS）之间的标准效度（Spearman相关系数）分别为-0.837和0.725。中文版的结构效度与原版相似。术后三个月的标准化反应均值和效应量分别为1.34和1.21，表明反应性高。通过Mann-Whitney U检验计算，该工具在区分有无鼻阻塞的受试者方面表现出出色的敏感性（P<0.01）。NOSE评分也与鼻阻力测量法测得的鼻阻力相关。
中文版NOSE成功地进行了跨文化调适和验证。因此，它可被推荐作为未来在中国测量鼻阻塞主观严重程度的有力工具。
