van Zijl Floris V W J, Timman Reinier, Datema Frank R
Department of Otolaryngology and Head and Neck Surgery, Erasmus University Medical Center, 's Gravendijkwal 230, P.O. 2040, 3000 CA, Rotterdam, The Netherlands.
Department of Medical Psychology and Psychotherapy, Erasmus University Medical Center, Rotterdam, The Netherlands.
Eur Arch Otorhinolaryngol. 2017 Jun;274(6):2469-2476. doi: 10.1007/s00405-017-4486-y. Epub 2017 Mar 3.
The nasal obstruction symptom evaluation (NOSE) scale is a validated disease-specific, self-completed questionnaire for the assessment of quality of life related to nasal obstruction. The aim of this study was to validate the Dutch (NL-NOSE) questionnaire. A prospective instrument validation study was performed in a tertiary academic referral center. Guidelines for the cross-cultural adaptation process from the original English language scale into a Dutch language version were followed. Patients undergoing functional septoplasty or septorhinoplasty and asymptomatic controls completed the questionnaire both before and 3 months after surgery to test reliability and validity. Additionally, we explored the possibility to reduce the NOSE scale even further using graded response models. 129 patients and 50 controls were included. Internal consistency (Cronbach's alpha 0.82) and test-retest reliability (intraclass correlation coefficient 0.89) were good. The instrument showed excellent between-group discrimination (Mann-Whitney U = 85, p < 0.001) and high response sensitivity to change (Wilcoxon rank p < 0.001). The NL-NOSE correlated well with the score on a visual analog scale measuring the subjective sensation of nasal obstruction, with exception of item 4 (trouble sleeping). Item 4 provided the least information to the total scale and item 3 (trouble breathing through nose) the most, particularly in the postoperative group. The Dutch version of the NOSE (NL-NOSE) demonstrated satisfactory reliability and validity. We recommend the use of the NL-NOSE as a validated instrument to measure subjective severity of nasal obstruction in Dutch adult patients.
鼻阻塞症状评估（NOSE）量表是一种经过验证的针对特定疾病的自我完成问卷，用于评估与鼻阻塞相关的生活质量。本研究的目的是验证荷兰语版（NL-NOSE）问卷。在一家三级学术转诊中心进行了一项前瞻性工具验证研究。遵循了将原始英语量表跨文化改编为荷兰语版本的指南。接受功能性鼻中隔成形术或鼻中隔鼻成形术的患者以及无症状对照者在手术前和手术后3个月均完成了问卷，以测试信度和效度。此外，我们探索了使用等级反应模型进一步简化NOSE量表的可能性。纳入了129例患者和50例对照者。内部一致性（Cronbach's alpha 0.82）和重测信度（组内相关系数0.89）良好。该工具显示出出色的组间区分能力（Mann-Whitney U = 85，p < 0.001）和对变化的高反应敏感性（Wilcoxon秩和检验p < 0.001）。NL-NOSE与测量鼻阻塞主观感觉的视觉模拟量表得分相关性良好，但第4项（睡眠困难）除外。第4项对总分提供的信息最少，而第3项（经鼻呼吸困难）提供的信息最多，尤其是在术后组中。荷兰语版的NOSE（NL-NOSE）表现出令人满意的信度和效度。我们建议使用NL-NOSE作为一种经过验证的工具，来测量荷兰成年患者鼻阻塞的主观严重程度。
