Salles Cristina, Bispo Marcelo, Trindade-Ramos Regina Terse
Faculdade de Medicina, Universidade Federal da Bahia (UFBA), Salvador, BA, Brazil.
Faculdade de Medicina, Universidade Federal da Bahia (UFBA), Salvador, BA, Brazil.
J Pediatr (Rio J). 2014 Jul-Aug;90(4):420-5. doi: 10.1016/j.jped.2014.01.005. Epub 2014 Mar 28.
to evaluate associations between morphometric variables, cervical circumference (CC), and abdominal circumference (AC) with the presence of nocturnal desaturation in children and adolescents with sickle-cell anemia.
all patients were submitted to baseline polysomnography, oral cavity measurements (maxillary intermolar distance, mandibular intermolar distance, and overjet), and CC and AC measurements.
a total of 85 patients were evaluated. A positive correlation was observed between the height/age Z-score and CC measurement (r = 0.233, p = 0.031). The presence of nocturnal desaturation was associated with CC (59.2± 9.3 vs. 67.5 ± 10.7, p = 0.006) and AC measurements (27.0 ± 2.0 vs. 29.0± 2.1, p = 0.028). There was a negative correlation between desaturation and maxillary intermolar distance (r = -0.365, p = 0.001) and mandibular intermolar distance (r = -0.233, p = 0.037).
the morphometric variables of CC and AC may contribute to raise suspicion of nocturnal desaturation in children and adolescents with sickle-cell anemia.
评估形态学变量、颈围（CC）和腹围（AC）与镰状细胞贫血儿童及青少年夜间血氧饱和度降低之间的关联。
所有患者均接受了基线多导睡眠图检查、口腔测量（上颌磨牙间距离、下颌磨牙间距离和覆盖）以及CC和AC测量。
共评估了85例患者。身高/年龄Z评分与CC测量值之间存在正相关（r = 0.233，p = 0.031）。夜间血氧饱和度降低与CC（59.2±9.3 vs. 67.5±10.7，p = 0.006）和AC测量值（27.0±2.0 vs. 29.0±2.1，p = 0.028）相关。血氧饱和度降低与上颌磨牙间距离（r = -0.365，p = 0.001）和下颌磨牙间距离（r = -0.233，p = 0.037）之间存在负相关。
CC和AC的形态学变量可能有助于提高对镰状细胞贫血儿童及青少年夜间血氧饱和度降低的怀疑。
