Góis Carlos Rodolfo Tavares de, D'Ávila Jeferson Sampaio, Cipolotti Rosana, Lira Amanda da Silva, Silva Ana Letícia Leite
Department of Medicine, Universidade Federal de Sergipe (UFS), Aracaju, SE, Brazil.
Department of Statistics and Actuarial Sciences, Universidade Federal de Sergipe (UFS), São Cristóvão, SE, Brazil.
Int Arch Otorhinolaryngol. 2018 Jan;22(1):55-59. doi: 10.1055/s-0037-1602702. Epub 2017 May 2.
Adenotonsillar hypertrophy is more common in children with sickle cell disease, and can lead to sleep-disordered breathing. To determine the frequency of adenotonsillar hypertrophy in pre-school children with sickle cell disease and assess the diagnostic accuracy of the sleep-disordered breathing subscale in the Sleep Disturbance Scale for Children. Observational study with a group of 48 children with sickle cell disease and a control group of 35 children without the disease. The children underwent oropharingoscopy and video nasal endoscopy. The parents and/or guardians answered the questions of the subscale. Adenotonsillar hypertrophy was observed in 25% of the children in the study group, and in 20% of the children in the control group, with no statistical difference between the groups. The subscale score ranged from 3 to 11 in both groups. There was a statistical significance in the study group. The average was 4.79 (standard deviation [SD] ± 2.50), with 4.19 (SD ± 1.72) among the children without adenotonsillar hypertrophy, and 6.5 (SD ± 3.40) among the children with adenotonsillar hypertrophy. There was also a statistical significance in the control group. The average was 5.23 (SD ± 2.81), with 4.44 (SD ± 2.2) among the children without adenotonsillar hypertrophy, and 7.87 (SD ± 2.89) among the children with adenotonsillar hypertrophy. Adenotonsillar hypertrophy was not associated with sickle cell disease in pre-school children. The subscale of sleep-disordered breathing in the Sleep Disturbance Scale for Children was a useful tool for the diagnostic suspicion of adenotonsillar hypertrophy in children in this age group.
腺样体扁桃体肥大在镰状细胞病患儿中更为常见，并可导致睡眠呼吸障碍。为了确定学龄前镰状细胞病患儿腺样体扁桃体肥大的发生率，并评估儿童睡眠障碍量表中睡眠呼吸障碍子量表的诊断准确性。对一组48名镰状细胞病患儿和一组35名无该病的对照组儿童进行观察性研究。这些儿童接受了口咽镜检查和视频鼻内镜检查。父母和/或监护人回答了子量表的问题。研究组25%的儿童观察到腺样体扁桃体肥大，对照组20%的儿童观察到腺样体扁桃体肥大，两组之间无统计学差异。两组子量表得分范围均为3至11分。研究组有统计学意义。平均分为4.79（标准差[SD]±2.50），无腺样体扁桃体肥大的儿童平均分为4.19（SD±1.72），有腺样体扁桃体肥大的儿童平均分为6.5（SD±3.40）。对照组也有统计学意义。平均分为5.23（SD±2.81），无腺样体扁桃体肥大的儿童平均分为4.44（SD±2.2），有腺样体扁桃体肥大的儿童平均分为7.87（SD±2.89）。腺样体扁桃体肥大与学龄前儿童的镰状细胞病无关。儿童睡眠障碍量表中的睡眠呼吸障碍子量表是该年龄组儿童腺样体扁桃体肥大诊断怀疑的有用工具。
