周围神经导管减少翻修全膝关节置换术后阿片类药物的使用及疼痛

Peripheral Nerve Catheter Reduces Postoperative Opioid Consumption and Pain in Revision Total Knee Arthroplasty.

作者信息

Arraut Jerry, Thomas Jeremiah, Oakley Christian, Umeh Uchenna O, Furgiuele David L, Schwarzkopf Ran

机构信息

Department of Orthopedic Surgery, NYU Langone Health, New York, NY, USA.

Department of Anesthesiology, Critical Care and Pain Medicine, Hospital for Special Surgery, New York, NY, USA.

出版信息

Arthroplast Today. 2023 Jun 12;22:101155. doi: 10.1016/j.artd.2023.101155. eCollection 2023 Aug.

Abstract

BACKGROUND

Patients undergoing revision total knee arthroplasty (rTKA) have historically received high doses of opioids during the perioperative period. As awareness of opioid use has heightened, opioid administration has continuously decreased. This study aimed to evaluate if peripheral nerve catheter (PNC) use in rTKA reduces opiate consumption while maintaining similar pain control and postoperative function levels.

METHODS

A retrospective review of 354 patients who underwent rTKA between July 2019 and January 2022 was conducted. Fifty total patients who received an adductor canal PNC were propensity-matched 1:1 to a control group of 50 patients that did not receive a PNC. To assess the primary outcome of opiate consumption, nursing documented opiate administration events were converted into morphine milligram equivalents per 24-hour interval. Postoperative pain and functional status were assessed using the verbal rating scale for pain and the Activity Measure for Post-Acute Care scores, respectively.

RESULTS

Compared to the control group, the PNC group demonstrated significantly lower overall inpatient opiate consumption (98.68 ± 117.03 vs 176.69 ± 203.47 morphine milligram equivalents; 44.15% decrease,  = .021) and lower verbal rating scale pain scores at 60 to 72 hours postoperatively (4.85 ± 1.24 vs 5.83 ± 1.35; 16.81% decrease,  = .038). There was no significant difference in Activity Measure for Post-Acute Care scores postoperatively (raw score: 19.41 ± 3.61 vs 19.46 ± 3.18; 0.26% decrease,  = .952). Finally, the PNC cohort was significantly less likely to be readmitted within 90 days after surgery (0.0% vs 12.0%;  = .012).

CONCLUSIONS

In rTKA patients, PNC can significantly reduce inpatient opioid consumption while maintaining a comparable functional recovery and superior pain control.

LEVEL III EVIDENCE

Retrospective Cohort Study.

摘要

背景

在历史上,接受全膝关节置换翻修术(rTKA)的患者在围手术期会使用高剂量的阿片类药物。随着对阿片类药物使用的关注度提高,阿片类药物的使用量持续下降。本研究旨在评估在rTKA中使用外周神经导管(PNC)是否能在维持相似的疼痛控制和术后功能水平的同时减少阿片类药物的消耗。

方法

对2019年7月至2022年1月期间接受rTKA的354例患者进行回顾性研究。将50例接受内收肌管PNC的患者与50例未接受PNC的对照组患者进行1:1倾向匹配。为评估阿片类药物消耗的主要结局,护理记录的阿片类药物给药事件被转换为每24小时间隔的吗啡毫克当量。分别使用疼痛视觉模拟评分和急性后期护理活动量表评估术后疼痛和功能状态。

结果

与对照组相比,PNC组的总体住院阿片类药物消耗量显著降低(98.68±117.03 vs 176.69±203.47吗啡毫克当量;降低44.15%,P=.021),且术后60至72小时的疼痛视觉模拟评分更低(4.85±1.24 vs 5.83±1.35;降低16.81%,P=.038)。术后急性后期护理活动量表评分无显著差异(原始评分:19.41±3.61 vs 19.46±3.18;降低0.26%,P=.952)。最后,PNC队列在术后90天内再次入院的可能性显著更低(0.0% vs 12.0%;P=.012)。

结论

在rTKA患者中,PNC可显著降低住院期间阿片类药物的消耗量,并维持相当的功能恢复和更好的疼痛控制。

三级证据

回顾性队列研究。

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