Diaphragm fiber strength is reduced in critically ill patients and restored by a troponin activator.
作者信息
Hooijman Pleuni E, Beishuizen Albertus, de Waard Monique C, de Man Frances S, Vermeijden J W, Steenvoorde Pascal, Bouwman R Arthur, Lommen Wies, van Hees Hieronymus W H, Heunks Leo M A, Dickhoff Chris, van der Peet Donald L, Girbes Armand R J, Jasper Jeff R, Malik Fady I, Stienen Ger J M, Hartemink Koen J, Paul Marinus A, Ottenheijm Coen A C
机构信息
1 VU University Medical Center Amsterdam, The Netherlands.
出版信息
Am J Respir Crit Care Med. 2014 Apr 1;189(7):863-5. doi: 10.1164/rccm.201312-2260LE.
Abstract
摘要
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本文引用的文献
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Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases.快速骨骼肌肌钙蛋白的激活作为治疗神经肌肉疾病的潜在治疗方法。
Nat Med. 2012 Feb 19;18(3):452-5. doi: 10.1038/nm.2618.
2
Optimal protein and energy nutrition decreases mortality in mechanically ventilated, critically ill patients: a prospective observational cohort study.最佳蛋白质和能量营养可降低机械通气危重症患者的死亡率：一项前瞻性观察性队列研究。
JPEN J Parenter Enteral Nutr. 2012 Jan;36(1):60-8. doi: 10.1177/0148607111415109. Epub 2011 Dec 13.
3
Selective diaphragm muscle weakness after contractile inactivity during thoracic surgery.胸部手术后收缩活动期间选择性膈肌肌无力。
Ann Surg. 2011 Dec;254(6):1044-9. doi: 10.1097/SLA.0b013e318232e75b.
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Diaphragm muscle weakness in an experimental porcine intensive care unit model.实验性猪重症监护病房模型中的膈肌肌无力。
PLoS One. 2011;6(6):e20558. doi: 10.1371/journal.pone.0020558. Epub 2011 Jun 15.
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Diaphragm muscle fiber function and structure in humans with hemidiaphragm paralysis.膈肌瘫痪患者膈肌肌纤维功能和结构。
Am J Physiol Lung Cell Mol Physiol. 2011 Aug;301(2):L228-35. doi: 10.1152/ajplung.00040.2011. Epub 2011 May 27.
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Rapidly progressive diaphragmatic weakness and injury during mechanical ventilation in humans.在人类机械通气过程中迅速进展的膈肌无力和损伤。
Am J Respir Crit Care Med. 2011 Feb 1;183(3):364-71. doi: 10.1164/rccm.201004-0670OC. Epub 2010 Sep 2.
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Mechanical ventilation-induced diaphragm disuse in humans triggers autophagy.机械通气导致的人体膈肌废用会引发自噬。
Am J Respir Crit Care Med. 2010 Dec 1;182(11):1377-86. doi: 10.1164/rccm.201002-0234OC. Epub 2010 Jul 16.
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Increased duration of mechanical ventilation is associated with decreased diaphragmatic force: a prospective observational study.机械通气时间延长与膈肌力量下降有关：一项前瞻性观察研究。
Crit Care. 2010;14(4):R127. doi: 10.1186/cc9094. Epub 2010 Jul 1.
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Caspase and calpain activation both contribute to sepsis-induced diaphragmatic weakness.半胱天冬酶和钙蛋白酶的激活均有助于脓毒症引起的膈肌无力。
J Appl Physiol (1985). 2009 Nov;107(5):1389-96. doi: 10.1152/japplphysiol.00341.2009. Epub 2009 Aug 6.
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Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans.机械通气患者膈肌纤维的快速废用性萎缩
N Engl J Med. 2008 Mar 27;358(13):1327-35. doi: 10.1056/NEJMoa070447.
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