真菌苯并呋喃酮：化学、生物学、生物合成与系统发育。

Fungal phenalenones: chemistry, biology, biosynthesis and phylogeny.

机构信息

Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Egypt.

出版信息

Nat Prod Rep. 2014 May;31(5):628-45. doi: 10.1039/c3np70088g. Epub 2014 Apr 1.

Abstract

Covering up to the end of August 2013. Phenalenones are members of a unique class of natural polyketides exhibiting diverse biological potential. This is a comprehensive review of 72 phenalenones with diverse structural features originating from fungal sources. Their bioactive potential and structure elucidation are discussed along with a review of their biosynthetic pathways and the taxonomical relationship between the fungi producing these natural products.

摘要

截止到 2013 年 8 月底，苯并菲咯酮是一类具有独特结构的天然聚酮化合物，具有多种生物活性。本文对 72 种真菌来源的苯并菲咯酮进行了综述，介绍了它们的结构特征、生物活性及其生物合成途径，并对产生这些天然产物的真菌的分类学关系进行了讨论。